Anti-hyperuricemia Effect of Water Fraction Cinnamon (Cinnamomum burmannii (Ness & T. Ness) Blume) on White Male Rats

Dwitiyanti, Dwitiyanti dan Ema, Dewanti dan Rizky Arcinthya Rachmania, Rizky Anti-hyperuricemia Effect of Water Fraction Cinnamon (Cinnamomum burmannii (Ness & T. Ness) Blume) on White Male Rats. Anti-hyperuricemia Effect of Water Fraction Cinnamon (Cinnamomum burmannii (Ness & T. Ness) Blume) on White Male Rats.

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Abstract

Hyperuricemia is a condition of increased concentration of uric acid in the blood. Cinnamon bark
(Cinnamomum burmannii (Ness & T. Ness) Blume) has been used empirically to decrease uric acid levels.
This research is to determine the effect of water fraction from cinnamon bark as anti-hyperuricemia. For
being in hyperuricemia condition, the rats were provided with high-purine food and potassium oxonate
50mg/200gBW as an uricase inhibitor. As many as 4,108 mg dose/200gBW of Allopurinol was used as a
comparison for positive control. The dose of cinnamon bark used was 104 mg/200g BW for the first group,
208 mg/200g BB for the second group and 416 mg/200gBW for the third group. The result shows that the
second group can lower uric acid level (58,87%) and has a similar result with the positive group (P>0.05). It
concludes that the water fraction of cinnamon bark has antihyperuricemia effect.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Keguruan & Ilmu Pendidikan > Pendidikan Ekonomi
Depositing User: Furqon FFS
Date Deposited: 19 Dec 2019 05:50
Last Modified: 19 Dec 2019 05:50
URI: http://repository.uhamka.ac.id/id/eprint/810

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