Effect of Using the Combination of Tween 80 and Ethanol on the Forming and Physical Stability of Microemulsion of Eucalyptus Oil as Antibacterial

Rahma, Elfiyani dan Anisa Amalia, Anisa dan Septian Yudi Pratama, Septian Effect of Using the Combination of Tween 80 and Ethanol on the Forming and Physical Stability of Microemulsion of Eucalyptus Oil as Antibacterial. Effect of Using the Combination of Tween 80 and Ethanol on the Forming and Physical Stability of Microemulsion of Eucalyptus Oil as Antibacterial.

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Abstract

Objective: The purpose of this study was to determine the effect of increasing
concentrations of the combination of tween 80 and ethanol to the formation
and stability of the physical properties of eucalyptus oil microemulsion. Methods:
This oil is formulated into a microemulsion by increasing the concentration
of the combination of tween 80 and ethanol (1: 1) with various concentrations,
ie 40%, 45%, and 50% as a component of surfactant and cosurfactant. The
evaluation was done for 8 weeks covering organoleptic test, test phase separation,
viscosity test, measurement of pH, density measurements, measurements
of surface tension and particle size measurement. Results: The pH of
micro-emulsion showed in the range 5.4 to 6.2. Viscosity results obtained viscosity
values between 206.2 to 248 cps. Density measurement results were
between 0.9839 to 0.9904 g/ml. The results of surface tension measurement
results obtained between 35.83 to 37.10 dyne/cm. The results of particle size
measurement results obtained from 23.83 to 30.43 nm. Conclusion: It can be
concluded that the use of tween 80 and ethanol can form a microemulsion system
of eucalyptus oil, and with increasing concentrations of the combination
of tween 80 and ethanol can increase the stability of the physical properties of
the micro-emulsion system.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Keguruan & Ilmu Pendidikan > Pendidikan Ekonomi
Depositing User: Furqon FFS
Date Deposited: 19 Dec 2019 05:48
Last Modified: 19 Dec 2019 05:48
URI: http://repository.uhamka.ac.id/id/eprint/776

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