Acute Oral Toxicity Test of Nicotiana tabacum L. Bio-Oil Against Female Winstar Rats

H N Andjani, Andjani dan Y Sentosa, Sentosa dan YATI, KORI dan A Fauzantoro, Fauzantoro dan M Gozan, Gozan dan Y J Yoo, Yoo Acute Oral Toxicity Test of Nicotiana tabacum L. Bio-Oil Against Female Winstar Rats. IOP Conference Series: Earth and Environmental Science.

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Abstract

Tobacco plants are notably known for its pesticidal properties, particularly due to its
nicotine content. In this study, Nicotiana tabacum L. bio-oil was obtained using pyrolysis
technique. The safety of the bio-oil to be used as bioinsecticide was analyzed through acute oral
toxicity test by administering 5000 mg bio-oil/kg body weight of female winstar rats that were
analogous to humans. It was concluded that the bio-oil was not toxic due to absence of mortality
and no significant change in the body weight and behavior of the rats.

Item Type: Article
Subjects: H Social Sciences
Divisions: Fakultas Farmasi dan Sains
Depositing User: Furqon FFS
Date Deposited: 18 Dec 2019 04:56
Last Modified: 02 Nov 2020 08:34
URI: http://repository.uhamka.ac.id/id/eprint/745

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