Hanani, Endang dan Sri Harsodjo, Sri dan Hayati, hayati dan Nellysa Revita, Nellysa Pharmacognostical and Preliminary Phytochemical Evaluation of Cordia sebestena L. Pharmacognostical and Preliminary Phytochemical Evaluation of Cordia sebestena L..
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Abstract
Cordia sebestena L. belongs to family Boraginaceae is commonly known as
“Geiger Tree” in Indonesia, it is generally found in Indonesia included Jakarta, and many
other countries. Some researchers have revealed the presence of several pharmacology
activities. Thus this study is an attempt to present an overview of pharmacognostic and
phytochemical evaluation reported on this plant. Objective: In the present investigation, various
pharmacognostic standards have been investigated to prove the authenticity of the plant for
the claimed traditional uses. This will help in the identification of powder drug prior to using in
medicine. Methods: Macroscopic, microscopic and physicochemical evaluation, of the drug
was performed using standardized procedures as mentioned in the WHO and Indonesian
Herb Pharmacopoeia
guidelines.Thin layer chromatography profile was done using some
different mobile phase system to the identification of the drug. Results: The physicochemical
parameters such as moisture content, ethanol- and water-soluble extractive, total ash, acidinsoluble
ash value, were determined. Phytochemical screening showed the presence of
alkaloids, flavonoids, phenols, saponins, tannins, steroids, terpenoids in the ethanolic extracts
of leaf of this plant. The TLC profile of n-hexane, dichloromethane and methanol extract were
carried out 5, 7 and 2 spots respectively. Conclusion: The present study on pharmacognostical,
physicochemical and phytochemical standards could be useful information for authentication
and preparation monograph for C.sebestena.
| Item Type: | Article |
|---|---|
| Subjects: | H Social Sciences |
| Divisions: | Fakultas Farmasi dan Sains |
| Depositing User: | Furqon FFS |
| Date Deposited: | 18 Dec 2019 04:56 |
| Last Modified: | 02 Nov 2020 07:09 |
| URI: | http://repository.uhamka.ac.id/id/eprint/733 |
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