The Anti-Inflammatory Activity of Nigella sativa Balm Sticks

Lusi, Putri Dwita dan YATI, KORI dan Sri, Nevi Gantini The Anti-Inflammatory Activity of Nigella sativa Balm Sticks. The Anti-Inflammatory Activity of Nigella sativa Balm Sticks.

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Abstract

Nigella sativa oil has been known to have potent anti-inflammatory activity. This research
aimed to determine the anti-inflammation activity of Nigella sativa oil in a simple balm stick by topical
application. The activity was checked using two methods: carrageenan-induced paw oedema and
granuloma pouch on rats. The results showed that balm sticks which contained 10% Nigella sativa
could overcome both acute and sub-acute inflammation showing by high oedema inhibition (60.64%),
low leucocytes count (43.55% lower than control) as well as a notable TNF-� concentration (50%
lower than control) on the inflamed area. In conclusion, topical application of a Nigella sativa balm
stick was effective for both acute and sub-acute forms of inflammation.

Item Type: Article
Subjects: H Social Sciences
Divisions: Fakultas Farmasi dan Sains
Depositing User: Furqon FFS
Date Deposited: 22 Jan 2019 07:42
Last Modified: 26 Oct 2020 07:33
URI: http://repository.uhamka.ac.id/id/eprint/614

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