Siska, Siska (2015) SUBCHRONIC TOXICITY TEST OF COMBINATION OF GINGER (Zingiber officinale Rosc.) EXTRACT AND ZINC ON SWISS WEBSTER MICE. Proceding International Seminar FFS UHAMKA. pp. 157-164. ISSN 978-602-71959-0-5
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Abstract
The combination of ginger (Zingiber officinale Rosc.) extract and zinc has the effect of
lowering levels of glucose. triglycerides. cholesterol and anti-oxidants. This study aimed
to determine the safety administration of combination ginger extract and zinc. through
the subchronic toxicity test. Parameters measured were body weight. liver and kidney
histopathology. SGOT. and SGPT. The study used a sample of 20 male mice. divided into
one control group and one treatment group. The extract was given orally through a sonde
for 75 days. The treatment group was given a combination of ginger extract and zinc
(ginger 30mg / 20g BW + zinc 0.4mg / 20g BW ) and the control group was given water.
After 75 days of treatment sample blood the heart and then checked SGOT and SGPT.
The collected statistical results with the method of independent samples T-test showed
no significant difference between the levels of SGOT and SGPT control group to the
treatment group. It can be concluded the combination of ginger extract and zinc did not show
any toxic effects in subchronic and did not cause toxicity and damage to vital organs, such as liver and kidney
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > Q Science (General) |
| Divisions: | Fakultas Farmasi dan Sains |
| Depositing User: | Supandi Supandi |
| Date Deposited: | 30 Dec 2020 13:10 |
| Last Modified: | 09 Aug 2021 14:59 |
| URI: | http://repository.uhamka.ac.id/id/eprint/5070 |
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