Hadi Sunaryo, Hadi dan Siska, Siska Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L. EUROPEAN PHARMACEUTICAL JOURNAL.
Preview |
Text
European Pharmaceutical Journal Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L..pdf Download (291kB) | Preview |
Abstract
Trees and shrubs of the genus Cordia are widely distributed in the warmer regions, including Indonesia. The aim of this study
was to evaluate the analgesic and anti-inflammatory properties of the ethanolic extract of plant leaves in Wistar albino rats.
The analgesic activity was evaluated using the hot plate method and acetic acid-induced writhing, and the anti-inflammatory
activity was determined using carrageenan-induced paw oedema. The results showed that the Cordia sebestena ethanol extract
(100, 200 and 400 mg/kg) exhibited significant analgesic effects in a dose-dependent manner in the two pain models tested. The
extract also exhibited significant anti-inflammatory effects in the carrageenan-induced inflammation test. The data obtained
support the traditional folklore therapeutic claim about its analgesic and anti-inflammatory properties. Nonetheless, further
scientific investigation is required to establish its analgesic and anti-inflammatory properties in other experimental models and
clinical settings.
| Item Type: | Article |
|---|---|
| Subjects: | D History General and Old World > Fakultas Farmasi dan Sains |
| Divisions: | Fakultas Farmasi dan Sains > Farmasi |
| Depositing User: | Furqon FFS |
| Date Deposited: | 24 Nov 2025 08:22 |
| Last Modified: | 24 Nov 2025 08:22 |
| URI: | http://repository.uhamka.ac.id/id/eprint/48479 |
Actions (login required)
 |
View Item |
Altmetric
Altmetric