The Effect of Long Exposure Reed Diffuser Essential Oil Plumeria alba on Cortisol Levels of Male Wistar Rats

Siska, Siska (2023) The Effect of Long Exposure Reed Diffuser Essential Oil Plumeria alba on Cortisol Levels of Male Wistar Rats. The Effect of Long Exposure Reed Diffuser Essential Oil Plumeria alba on Cortisol Levels of Male Wistar Rats, 6 (2). pp. 120-124. ISSN 2621-4814

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Abstract

Stress can occur due to a person's inability to respond to a stressor,
resulting in bodily or mental disorders. Anxiety can be
characterized by increased levels of cortisol, which is regulated by
the Hypothalamus-Pituitary-Adrenaline (HPA-axis).
Aromatherapy is a therapy using essential oils that give a distinctive
aroma to plant parts such as flowers, roots, leaves, and stems.
Aromatherapy can be done through a reed diffuser. The frangipani
(Plumeria alba) is one of the plants in Indonesia that has a particular
scent in its flowers. This study aims to determine the effect of
prolonged exposure to P. alba essential oil reed diffuser on cortisol
levels in rats. Twenty-four rats were divided into four groups: the
control group without exposure to a reed diffuser for 5 and 10 days
and the other group with exposure for 5 and 10 days. Each blood
was drawn through the retro-orbital, centrifuged to obtain serum,
and tested using LC-MS to determine cortisol levels. The group with
ten days of essential oil exposure showed lower cortisol levels. It
can be concluded that the duration of aromatherapy exposure is
connected to cortisol levels and that aromatherapy can be utilized
as a stress-reduction therapy

Item Type: Article
Subjects: Q Science > Q Science (General)
Divisions: Fakultas Farmasi dan Sains > Profesi Apoteker
Depositing User: Supandi Supandi
Date Deposited: 17 Feb 2024 06:23
Last Modified: 17 Feb 2024 06:23
URI: http://repository.uhamka.ac.id/id/eprint/33289

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