The Anti-Inflammatory Activity of Nigella sativa Balm Sticks

Lusi, Putri Dwita and YATI, KORI and Sri, Nevi Gantini The Anti-Inflammatory Activity of Nigella sativa Balm Sticks. The Anti-Inflammatory Activity of Nigella sativa Balm Sticks.

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Abstract

Nigella sativa oil has been known to have potent anti-inflammatory activity. This research aimed to determine the anti-inflammation activity of Nigella sativa oil in a simple balm stick by topical application. The activity was checked using two methods: carrageenan-induced paw oedema and granuloma pouch on rats. The results showed that balm sticks which contained 10% Nigella sativa could overcome both acute and sub-acute inflammation showing by high oedema inhibition (60.64%), low leucocytes count (43.55% lower than control) as well as a notable TNF-� concentration (50% lower than control) on the inflamed area. In conclusion, topical application of a Nigella sativa balm stick was effective for both acute and sub-acute forms of inflammation.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: Furqon furqon furqon
Date Deposited: 22 Jan 2019 07:42
Last Modified: 22 Jan 2019 07:42
URI: http://repository.uhamka.ac.id/id/eprint/614

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