AKTIVITAS EKSTRAK JAHE GAJAH (Zingiber officinaie) DENGAN ZINC TERHADAP KADAR GLUKOSA DARAH MENCIT YANG DIINDUKSI STREPTOZOTOCIN DAN PAKAN HIPERKOLESTEROL

Hadi Sunaryo, Hadi dan Siska, Siska dan Dwitiyanti, Dwitiyanti dan Rizky A.R, Rizky dan Helmi, Helmi (2013) AKTIVITAS EKSTRAK JAHE GAJAH (Zingiber officinaie) DENGAN ZINC TERHADAP KADAR GLUKOSA DARAH MENCIT YANG DIINDUKSI STREPTOZOTOCIN DAN PAKAN HIPERKOLESTEROL. Magra, 2 (2). pp. 29-35. ISSN 2302-772X

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Abstract

Ginger rhizome is a pari of the ginger plant that can he used for the treatment. Ginger extracts proven to lower blood glucose levels. The objective of this research to determine the activity of ginger extract (Zingiber officinale) in combination with zinc as antihyperglycemic. Male mice DDW were divided into 8 treatment groups, each consisting of 6 mice. Group I ( normal control) , group II ( negative control) , group III (positive control) were given metformin , group IV, and V, were given doses of ginger extract 0, 75 mg/20g mice and zinc 0.4 mg/20g mice, group VI, VII, and VIII , were given ginger extract at a dose of 0. 75 mg/20g mice + zinc at a dose 0,4 mg/20g mice , 1.5 mg/20g mice + 0,4 mg/20g mice , 3 mg / 20g mice + 0,4 mg/20g mice, respectively. Test animals fed cholesterol for 28 days and streptozotocin induced on day 14 , and then given a dose of ginger extract and comparator drug for 14 days. Blood sampling was done on days 29 and 44. Blood glucose test results showed ginger extract combination dose of 1.5 mg/20g mice and zinc doses 0.4 mg/20g mice were able to lower blood glucose levels comparable to metformin dose of 1.3 mg/20 g mice.

Item Type: Article
Subjects: Q Science > Q Science (General)
Depositing User: admin repository uhamka
Date Deposited: 28 May 2018 07:52
Last Modified: 28 May 2018 07:52
URI: http://repository.uhamka.ac.id/id/eprint/489

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