Sunda porcupine (Hystrix javanica F. Cuvier 1823) is an endemic mammalian fauna from Indonesia known as
a pest since they damage crops like corn and tubers. Local people hunt the porcupine to decrease the damage, but others
hunt for its medicinal benefits. They believe that sunda porcupine has medicinal benefits, yet this ethnomedicine has not
been recorded well and has no sufficient scientific report. One of the interesting ethnomedicines is that local people
believe the quills of sunda porcupine can treat toothache. Our research aims to add a scientific record of the sunda
porcupine’s quills as well the acute toxicity effect of sunda porcupine’s quills crude extract on male Sprague Dawley rats.
The extraction of the active compound of the quills was using ethanol 70%. The determination of acute toxicity effect
was using a fixed dose method by oral administration, including two steps: sighting study and main study, with four
doses: 5 mg/kg; 50 mg/kg; 300 mg/kg; and 2.000 mg/kg. We also observed the histological effect on liver and kidney
tissues. The result showed that the oral administration of the sunda porcupine’s quills crude extract by the method of the
fixed dose does not cause death in all rats used both after 24 hours (acute effect) and 14 days (delayed effect). Based on
the fixed dose method, we can categorize the sunda porcupine’s quills crude extract as non-toxic. Although the rats were
clinically healthy and showed no symptoms of intoxication during 14 days of observation, histopathological analysis of
the liver and kidney showed lesions which cannot be ignored. Histopathological analysis showed that the higher the dose,
the lesions tended to increase the severity on the liver and kidney, but the active substance administered did not kill the
rats and the severity was mostly mild. It is in line with the percentage of body weight gain, which is a group of placebo >
300 mg/kg > 2000 mg/kg, which may occur because the body prioritizes repairing the damage of the tissues due to the
exact administration rather than for growth. These findings can be used as consideration for further toxicity study on
sunda porcupine’s quills crude extract, such as chronic and subchronic toxicity tests, both to ensure the safety and to
complete the toxicity study of the extract.
Madu Indonesia memiliki kadar air yang cukup tinggi dan seringkali melebihi batas maksimal standar kualitas
madu berdasarkan regulasi nasional dan internasional. Hal ini disebabkan oleh kelembaban udara yang cukup
tinggi dan karakter higroskopis madu. Provinsi Riau merupakan salah satu penghasil madu tertinggi di
Indonesia, namun kadar airnya cukup tinggi yaitu pada rentang 23-27%. Salah satu upaya untuk mengurangi
kadar air madu adalah dengan pemanasan, namun senyawa metabolit sekunder pada madu berisiko mengalami
kerusakan dan berdampak pada penurunan sifat fungsional madu terhadap kesehatan. Penelitian terkait
pengaruh pemanasan terhadap stabilitas senyawa metabolit sekunder pada madu belum banyak dilakukan.
Penelitian ini bertujuan untuk melihat pengaruh pemanasan terhadap stabilitas senyawa metabolit sekunder
pada madu Apis mellifera hutan akasia dari Provinsi Riau, Indonesia, diantaranya analisis kadar air, penapisan
senyawa metabolit sekunder, pengukuran aktivitas antioksidan, pengukuran TPC dan pengukuran TFC. Hasil
penelitian menunjukkan bahwa perlakuan panas 50oC selama 5 hari dan perlakuan panas 105oC selama 6 jam
dapat menurunkan kadar air madu tanpa mengganggu stabilitas senyawa metabolit sekunder pada madu. Hal ini
ditunjukkan pada nilai IC50 madu tanpa perlakuan (21103,74 μg/mL) yang lebih besar dari madu dengan
perlakuan 50oC (16503,83 μg/mL) dan 105oC (777,33 μg/mL). Nilai IC50 yang rendah menunjukkan aktivitas
antioksidan yang tinggi, sejalan dengan TPC dan TFC. Nilai TPC dan TFC sampel tanpa perlakuan (TPC=
0,67 mgGAE/g; TFC=0,34 mgQE/g) lebih rendah dari sampel dengan pemanasan 50oC (TPC=1,59 mgGAE/g;
TFC=0,46 mgQE/g) dan lebih rendah dari sampel dengan pemanasan 105oC (TPC=13,94 mgGAE/g; TFC=4,37
mgQE/g)."
Penelitian ini bertujuan untuk mengetahui pengaruh pemberian tepung maggot (Hermetia illucens) terhadap pertumbuhan benih ikan lele Sangkuriang (Clarias sp.) di Greenhouse Universitas Muhammadiyah Prof. Dr. Hamka pada bulan Februari - Juli 2019. Metode penelitian yang digunakan adalah metode eksperimental dengan menggunakan desain penelitian Rancangan Acak Lengkap (RAL) yang terdiri dari 4 ulangan dan 6 perlakuan yaitu pemberian konsentrasi maggot 10% (P1), 20% (P2), 30% (P3), 40% (P4), 50% (P5) dan perlakuan kontrol (tanpa maggot). Parameter yang diamati pada penelitian ini adalah pertumbuhan berat mutlak (gr), pertumbuhan panjang mutlak (cm), pertumbuhan berat relatif (%) dan pertumbuhan panjang relatif (%). Hasil penelitian menunjukkan bahwa persentase maggot 30% dan tepung ikan 70% memberikan peningkatan pertumbuhan dan kelangsungan hidup yang baik bagi ikan lele Sangkuriang (Clarias sp.). Uji statistik pada taraf signifikan 5% menunjukkan bahwa pemberian pakan tepung maggot berpengaruh nyata (P>0,05) terhadap panjang mutlak, berat relatif dan panjang relatif namun tidak berpengaruh signifikan terhadap berat mutlak dan rasio efisiensi pakan. Secara umum pemberian tepung maggot dapat meningkatkan laju pertumbuhan ikan lele Sangkuriang (Clarias sp.) pada parameter pertumbuhan.
Background: The nutritional content of maggot Hermetia illucens L. is very good as a potential source of animal protein as an alternative to natural fish feed. Therefore maggot Hermetia illucens L. is very potential as a substitute for fish meal which is currently the main raw material for fish pellets. Our study sought to determine the effect of a combination of maggot flour and fish meal on the growth of Sangkuriang catfish (Clarias sp.). This research is a continuation of research that has been done in 2017 using fresh maggot as catfish feed and freshwater pomfret.
Methods: Data were performed using a completely randomized design (CRD) technique with 4 replications and 6 treatments of catfish seeds, namely giving maggot concentrations of 10% (P1), 20% (P2), 30% (P3), 40% ( P4), 50% (P5), control treatment (without maggot) and analyzed using ANAVA.
Results: The percentage of maggot 30% and 70% fish meal provide increased growth and good survival for Sangkuriang catfish (Clarias sp.). Statistical tests at a significant level of 5% showed that feeding maggot flour significantly (P> 0.05) on absolute length, relative weight and relative length but did not significantly influence the absolute weight and feed efficiency ratio.
Conclusions: Giving maggot flour can increase the growth rate of Sangkuriang catfish (Clarias sp.) On growth parameters.