eprintid: 904
rev_number: 9
eprint_status: archive
userid: 1193
dir: disk0/00/00/09/04
datestamp: 2020-02-12 04:48:31
lastmod: 2020-02-12 04:48:31
status_changed: 2020-02-12 04:48:31
type: article
metadata_visibility: show
creators_name: Akbar, Budhi
creators_name: Susilo, Susilo
creators_name: Ranti An Nissa, Ranti
creators_name: Rosi Feirina Ritonga, Rosi
creators_name: Suci Lestari, Suci
creators_name: Yuni Astuti, Yuni
creators_name: Parwito, Parwito
creators_id: susilo@uhamka.ac.id
corp_creators: UHAMKA
corp_creators: UHAMKA
title: Antifertility Effect of the Ethanol Extract of Centella asiatica L. Urban Against the White Rat (Rattus norvegicus L.) in the Early Post-Implantation
ispublished: pub
subjects: A
subjects: AS
divisions: sch_bio
abstract: Centella asiatica is commonly known as centella or pegagan is one of the biological
resources that have many benefits for mankind. Clinical and pharmacological study of Centella
asiatica has been widely proven by scientists of the world, but there are a few properties that
require further investigation in particular its effect on fertility. This research aims to know the
influence of the ethanol extract of pegagan (Centella asiatica) towards the birth rates or
fertility in the early post-implantation. On the research, white rat (Rattus norvegicus L.) is used
as animal tested. The method that used in this research was an experiment by using randomly
complete design. The tested animals were grouped into 4 treatment i.e. group I (control group),
group II (dose 175 mg/kg body weight), group III (a dose of 200 mg/kg body weight) and
Group IV (dose 225 mg/kg body weight). The tested animals were given the exraction of
Centella asiatica leaf orally with different doses for 15 days after post-implantation. The value
of post-implantation death percentage is calculated by counting the number of implantation,
either containing a live fetus, or dead fetus and embryo resorb. The results showed that
Centella asiatica gave the influ-ence on white white rat ferlitisation. On the grup IV treatment
with the dose of 225 mg/kg body weight showed the highest KPI val-ue i.e. 57.23%.
publisher: IOP Conf. Series: Journal of Physics
full_text_status: public
publication: Antifertility Effect of the Ethanol Extract of Centella asiatica L. Urban Against the White Rat (Rattus norvegicus L.) in the Early Post-Implantation
refereed: TRUE
citation:   Akbar, Budhi dan Susilo, Susilo dan Ranti An Nissa, Ranti dan Rosi Feirina Ritonga, Rosi dan Suci Lestari, Suci dan Yuni Astuti, Yuni dan Parwito, Parwito   Antifertility Effect of the Ethanol Extract of Centella asiatica L. Urban Against the White Rat (Rattus norvegicus L.) in the Early Post-Implantation.  Antifertility Effect of the Ethanol Extract of Centella asiatica L. Urban Against the White Rat (Rattus norvegicus L.) in the Early Post-Implantation.       
document_url: http://repository.uhamka.ac.id/id/eprint/904/1/Akbar_2018_J._Phys.__Conf._Ser._1114_012002.pdf