@article{repository904, publisher = {IOP Conf. Series: Journal of Physics}, journal = {Antifertility Effect of the Ethanol Extract of Centella asiatica L. Urban Against the White Rat (Rattus norvegicus L.) in the Early Post-Implantation}, title = {Antifertility Effect of the Ethanol Extract of Centella asiatica L. Urban Against the White Rat (Rattus norvegicus L.) in the Early Post-Implantation}, url = {http://repository.uhamka.ac.id/id/eprint/904/}, author = {Akbar, Budhi and Susilo, Susilo and Ranti An Nissa, Ranti and Rosi Feirina Ritonga, Rosi and Suci Lestari, Suci and Yuni Astuti, Yuni and Parwito, Parwito}, abstract = {Centella asiatica is commonly known as centella or pegagan is one of the biological resources that have many benefits for mankind. Clinical and pharmacological study of Centella asiatica has been widely proven by scientists of the world, but there are a few properties that require further investigation in particular its effect on fertility. This research aims to know the influence of the ethanol extract of pegagan (Centella asiatica) towards the birth rates or fertility in the early post-implantation. On the research, white rat (Rattus norvegicus L.) is used as animal tested. The method that used in this research was an experiment by using randomly complete design. The tested animals were grouped into 4 treatment i.e. group I (control group), group II (dose 175 mg/kg body weight), group III (a dose of 200 mg/kg body weight) and Group IV (dose 225 mg/kg body weight). The tested animals were given the exraction of Centella asiatica leaf orally with different doses for 15 days after post-implantation. The value of post-implantation death percentage is calculated by counting the number of implantation, either containing a live fetus, or dead fetus and embryo resorb. The results showed that Centella asiatica gave the influ-ence on white white rat ferlitisation. On the grup IV treatment with the dose of 225 mg/kg body weight showed the highest KPI val-ue i.e. 57.23\%.} }