eprintid: 876
rev_number: 8
eprint_status: archive
userid: 1193
dir: disk0/00/00/08/76
datestamp: 2020-02-04 09:15:38
lastmod: 2020-02-04 09:15:38
status_changed: 2020-02-04 09:15:38
type: article
metadata_visibility: show
creators_name: Hadi Sunaryo, Hadi
creators_name: Siska, Siska
creators_name: Hanani, Endang
creators_name: Anindita RS, Anindita
creators_name: Yanti N, Yanti
creators_name: Lisa, Lisa
creators_id: hadisunaryo@uhamka.ac.id
creators_id: siska@uhamka.ac.id
creators_id: endang_hanani@uhamka.ac.id
corp_creators: UHAMKA
corp_creators: UHAMKA
corp_creators: UHAMKA
title: Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L.
ispublished: pub
subjects: R1
subjects: RS
divisions: sch_med
abstract: Trees and shrubs of the genus Cordia are widely distributed in the warmer regions, including Indonesia. The aim of this study
was to evaluate the analgesic and anti-inflammatory properties of the ethanolic extract of plant leaves in Wistar albino rats.
The analgesic activity was evaluated using the hot plate method and acetic acid-induced writhing, and the anti-inflammatory
activity was determined using carrageenan-induced paw oedema. The results showed that the Cordia sebestena ethanol extract
(100, 200 and 400 mg/kg) exhibited significant analgesic effects in a dose-dependent manner in the two pain models tested. The
extract also exhibited significant anti-inflammatory effects in the carrageenan-induced inflammation test. The data obtained
support the traditional folklore therapeutic claim about its analgesic and anti-inflammatory properties. Nonetheless, further
scientific investigation is required to establish its analgesic and anti-inflammatory properties in other experimental models and
clinical settings.
publisher: EUROPEAN PHARMACEUTICAL JOURNAL
full_text_status: public
publication: Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L.
refereed: TRUE
citation:   Hadi Sunaryo, Hadi dan Siska, Siska dan Hanani, Endang dan Anindita RS, Anindita dan Yanti N, Yanti dan Lisa, Lisa   Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L.  Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L..       
document_url: http://repository.uhamka.ac.id/id/eprint/876/1/%5B24536725%20-%20European%20Pharmaceutical%20Journal%5D%20Evaluation%20of%20analgesic%20and%20anti-inflammatory%20activities%20of%20ethanolic%20extract%20of%20Cordia%20sebestena%20L..pdf