TY  - JOUR
TI  - Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L.
JF  - Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L.
PB  - EUROPEAN PHARMACEUTICAL JOURNAL
A1  - Hadi Sunaryo, Hadi
A1  - Siska, Siska
A1  - Hanani, Endang
A1  - Anindita RS, Anindita
A1  - Yanti N, Yanti
A1  - Lisa, Lisa
UR  - http://repository.uhamka.ac.id/id/eprint/876/
AV  - public
N2  - Trees and shrubs of the genus Cordia are widely distributed in the warmer regions, including Indonesia. The aim of this study
was to evaluate the analgesic and anti-inflammatory properties of the ethanolic extract of plant leaves in Wistar albino rats.
The analgesic activity was evaluated using the hot plate method and acetic acid-induced writhing, and the anti-inflammatory
activity was determined using carrageenan-induced paw oedema. The results showed that the Cordia sebestena ethanol extract
(100, 200 and 400 mg/kg) exhibited significant analgesic effects in a dose-dependent manner in the two pain models tested. The
extract also exhibited significant anti-inflammatory effects in the carrageenan-induced inflammation test. The data obtained
support the traditional folklore therapeutic claim about its analgesic and anti-inflammatory properties. Nonetheless, further
scientific investigation is required to establish its analgesic and anti-inflammatory properties in other experimental models and
clinical settings.
ID  - repository876
ER  -