eprintid: 875
rev_number: 7
eprint_status: archive
userid: 1193
dir: disk0/00/00/08/75
datestamp: 2020-02-04 09:15:36
lastmod: 2020-02-04 09:15:36
status_changed: 2020-02-04 09:15:36
type: article
metadata_visibility: show
creators_name: Hanifah, Rahmi
creators_name: Rizky Arcinthya Rachmania, Rizky
creators_name: Naniek Setiadi, Rajab
creators_id: hanifah_rahmi@uhamka.ac.id
corp_creators: UHAMKA
corp_creators: UHAMKA
corp_creators: UHAMKA
title: THE EFFECT OF SODIUM ALGINATE CONCENTRATION ON GREEN TEA
LEAF (Camellia sinensis L.) EXTRACT GEL AS TIROSINASE INHIBITOR
ispublished: pub
subjects: R1
subjects: RS
divisions: sch_med
abstract: Green tea leaf (Camellia sinensis L.) is a great plant containing polyphenol compounds
such as catechin and gallocatechin gallate that can be used as tyrosinase inhibitors. In
this study, the green tea leaf extract made into gel dosage form using sodium alginate as
a gelling agent. This research aimed to determine the effect of different sodium alginate
concentrations on the physical stability of gel extract green leaf and to know the effect of
gel formulation on tyrosinase inhibition. Gel made into 3 formulas with each
concentration of sodium alginate of 2; 2.5; 3%. The extraction of green tea leaves was
performed by reflux using 50% methanol solvent. The results showed that the three
formulas did not occur in phase separation, and had IC50 values of 34.80, 23.27, 20.69
μg/mL. The conclusion is gel dosage form with 3% sodium alginate gave the best
inhibition of tyrosinase with IC50 of 20.69 μg/mL.
full_text_status: public
publication: THE EFFECT OF SODIUM ALGINATE CONCENTRATION ON GREEN TEA LEAF (Camellia sinensis L.) EXTRACT GEL AS TIROSINASE INHIBITOR
refereed: TRUE
citation:   Hanifah, Rahmi dan Rizky Arcinthya Rachmania, Rizky dan Naniek Setiadi, Rajab   THE EFFECT OF SODIUM ALGINATE CONCENTRATION ON GREEN TEA LEAF (Camellia sinensis L.) EXTRACT GEL AS TIROSINASE INHIBITOR.  THE EFFECT OF SODIUM ALGINATE CONCENTRATION ON GREEN TEA LEAF (Camellia sinensis L.) EXTRACT GEL AS TIROSINASE INHIBITOR.       
document_url: http://repository.uhamka.ac.id/id/eprint/875/1/1904-4916-1-PB.pdf