%0 Journal Article
%A Hanifah, Rahmi
%A Rizky Arcinthya Rachmania, Rizky
%A Naniek Setiadi, Rajab
%A UHAMKA,
%A UHAMKA,
%A UHAMKA,
%F repository:875
%J THE EFFECT OF SODIUM ALGINATE CONCENTRATION ON GREEN TEA LEAF (Camellia sinensis L.) EXTRACT GEL AS TIROSINASE INHIBITOR
%T THE EFFECT OF SODIUM ALGINATE CONCENTRATION ON GREEN TEA  LEAF (Camellia sinensis L.) EXTRACT GEL AS TIROSINASE INHIBITOR
%U http://repository.uhamka.ac.id/id/eprint/875/
%X Green tea leaf (Camellia sinensis L.) is a great plant containing polyphenol compounds  such as catechin and gallocatechin gallate that can be used as tyrosinase inhibitors. In  this study, the green tea leaf extract made into gel dosage form using sodium alginate as  a gelling agent. This research aimed to determine the effect of different sodium alginate  concentrations on the physical stability of gel extract green leaf and to know the effect of  gel formulation on tyrosinase inhibition. Gel made into 3 formulas with each  concentration of sodium alginate of 2; 2.5; 3%. The extraction of green tea leaves was  performed by reflux using 50% methanol solvent. The results showed that the three  formulas did not occur in phase separation, and had IC50 values of 34.80, 23.27, 20.69  μg/mL. The conclusion is gel dosage form with 3% sodium alginate gave the best  inhibition of tyrosinase with IC50 of 20.69 μg/mL.