@article{repository870,
           title = {Potential Drug-Drug Interaction and Actual Adverse Event in
Hospitalized Geriatric Patients with Chronic Kidney Disease},
       publisher = {INTERNATIONAL CONFERENCE ON PHARMACEUTICAL RESEARCH AND PRACTICE},
         journal = {Potential Drug-Drug Interaction and Actual Adverse Event in Hospitalized Geriatric Patients with Chronic Kidney Disease},
        abstract = {Chronic kidney disease (CKD) in Indonesia often occurs in elderly (geriatric) patients
with various complications that cause polypharmacy which can increase the risk of drug-drug
interactions (DDIs). This study aimed to determine the incidence of DDIs and actual adverse
events in geriatric patients with CKD. This was a descriptive study where the samples were
collected retrospectively from medical record of the patients admitted in one tertiary care hospital
in Jakarta. Potential drug interaction was screened electronically using a drug interaction
checker (drugs.com) and manually by Drug Interaction Fact 2014. A total of 699 potential DDIs
were detected from 135 patients from one-year study period. The incidence of DDIs was 92.60\%
with 5.01\% actual adverse event detected due to DDIs. Pharmacodynamic interactions
accounted for 46.64\% with the most significant level at a moderate level (59.37\%). In conclusion,
The prevalence of DDIs in geriatric patients with CKD was found high and major level of
significance adverse event hyperkalemia was found caused by the DDIs.},
          author = {Nora Wulandari, Nora and Maifitrianti, Maifitrianti and Nila Yusmiati Ningsih, Nila},
             url = {http://repository.uhamka.ac.id/id/eprint/870/}
}