eprintid: 816
rev_number: 7
eprint_status: archive
userid: 1193
dir: disk0/00/00/08/16
datestamp: 2019-12-19 05:50:27
lastmod: 2019-12-19 05:50:27
status_changed: 2019-12-19 05:50:27
type: article
metadata_visibility: show
creators_name: Inding, Gusmayadi
creators_name: Priyanto, Priyanto
creators_id: indinggusmayadi@uhamka.ac.id
corp_creators: UHAMKA
corp_creators: UHAMKA
title: The Effect of Concentration Ratio of Gelatine and Polyvinylpyrrolidone as Binders on the Physical Properties of Red Ginger (Zingiber officinale Rosc.) Extract Lozenges
ispublished: pub
subjects: R1
subjects: RS
divisions: sch_med
abstract: Lozenges require the tablet hardness of 7-14 Kgf to be a suitable binder. Gelatine can be used to meet the
requirement as it creates granules with bad flow time. PVP produces granules with better flow time but it
takes a large quantity to reach the lozenges hardness desired. This study aimed to determine the effect of the
concentration ratio of gelatine and PVP as binders on the physical properties of red-ginger extract lozenges.
Lozenges made employing the wet granulation method following the ratio of gelatine and PVP of 1:1, 1:2,
1:3, 1:4 and 1:5. The hardness test results of the formula 1 to 5 are 9, 14, 16, 13 and 12 Kgf respectively and
the friability test results were 0,4%, 0,7%, 0,2%, 0,3% and 0,6% accordingly. The combination of gelatine
and PVP as binders provide a significant difference in the hardness and friability of the tablets.
publisher: In Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development (MICH-PhD 2018)
full_text_status: public
publication: The Effect of Concentration Ratio of Gelatine and Polyvinylpyrrolidone as Binders on the Physical Properties of Red Ginger (Zingiber officinale Rosc.) Extract Lozenges
refereed: TRUE
citation:   Inding, Gusmayadi dan Priyanto, Priyanto   The Effect of Concentration Ratio of Gelatine and Polyvinylpyrrolidone as Binders on the Physical Properties of Red Ginger (Zingiber officinale Rosc.) Extract Lozenges.  The Effect of Concentration Ratio of Gelatine and Polyvinylpyrrolidone as Binders on the Physical Properties of Red Ginger (Zingiber officinale Rosc.) Extract Lozenges.       
document_url: http://repository.uhamka.ac.id/id/eprint/816/1/MICH-PhD_2018_26.pdf