eprintid: 811
rev_number: 7
eprint_status: archive
userid: 1193
dir: disk0/00/00/08/11
datestamp: 2019-12-19 05:50:15
lastmod: 2019-12-19 05:50:15
status_changed: 2019-12-19 05:50:15
type: article
metadata_visibility: show
creators_name: N. T. Kartinah, Kartinah
creators_name: Abdullah Faizah, Abdullah
creators_name: Aguspadita Diah Ayu, Diah
creators_name: Tahyatul Bariroh, Tahyatul
corp_creators: UHAMKA
title: Low-Intensity Exercise Improves Neuroplasticity and
Spatial Memory on Young Adult of Male Wistar Rats
ispublished: pub
subjects: R1
subjects: RS
divisions: sch_med
abstract: Kartinah NT, Faizah A, Ayu AD, Tahyatu B. Low-Intensity Exercise
Improves Neuroplasticity and Spatial Memory on Young Adult of
Male Wistar Rats. JEPonline 2018;21(5):19-28. The purpose of this
study was to examine the effect of low-intensity exercise on
neuroplasticity and memory performance in young Wistar adult rats.
Neuroplasticity was determined by altering the expression of
proteins such as synaptophysin, neuroligin-1, AMPAR, NMDAR, and
PSD-95 in the rat hippocampus. Six-month-old rats were randomly
divided into Sedentary (Sed) and Exercise (Ex) Groups. Exercise
rats had better spatial memory compared to sedentary rats. This
result was shown by a reduction in both the time travelled and the
total error in the Water-E Maze task (P<0.05). Immunohistochemistry
staining showed that exercise rats had higher optical density scores
of both pre- and postsynaptic proteins compared to sedentary rats
(P<0.05). In conclusion, the findings indicate that the low-intensity
exercise improves spatial learning and memory, as shown by
increased neuroplasticity and synaptic maturation in young Wistar
adult rats.
publisher: Journal of Exercise Physiologyonline
full_text_status: public
publication: Low-Intensity Exercise Improves Neuroplasticity and Spatial Memory on Young Adult of Male Wistar Rats
refereed: TRUE
citation:   N. T. Kartinah, Kartinah dan Abdullah Faizah, Abdullah dan Aguspadita Diah Ayu, Diah dan Tahyatul Bariroh, Tahyatul   Low-Intensity Exercise Improves Neuroplasticity and Spatial Memory on Young Adult of Male Wistar Rats.  Low-Intensity Exercise Improves Neuroplasticity and Spatial Memory on Young Adult of Male Wistar Rats.       
document_url: http://repository.uhamka.ac.id/id/eprint/811/1/JEPonlineOCTOBER2018_Kartinah.pdf