relation: http://repository.uhamka.ac.id/id/eprint/811/
title: Low-Intensity Exercise Improves Neuroplasticity and  Spatial Memory on Young Adult of Male Wistar Rats
creator: N. T. Kartinah, Kartinah
creator: Abdullah Faizah, Abdullah
creator: Aguspadita Diah Ayu, Diah
creator: Tahyatul Bariroh, Tahyatul
subject: R Medicine (General)
subject: RS Pharmacy and materia medica
description: Kartinah NT, Faizah A, Ayu AD, Tahyatu B. Low-Intensity Exercise  Improves Neuroplasticity and Spatial Memory on Young Adult of  Male Wistar Rats. JEPonline 2018;21(5):19-28. The purpose of this  study was to examine the effect of low-intensity exercise on  neuroplasticity and memory performance in young Wistar adult rats.  Neuroplasticity was determined by altering the expression of  proteins such as synaptophysin, neuroligin-1, AMPAR, NMDAR, and  PSD-95 in the rat hippocampus. Six-month-old rats were randomly  divided into Sedentary (Sed) and Exercise (Ex) Groups. Exercise  rats had better spatial memory compared to sedentary rats. This  result was shown by a reduction in both the time travelled and the  total error in the Water-E Maze task (P<0.05). Immunohistochemistry  staining showed that exercise rats had higher optical density scores  of both pre- and postsynaptic proteins compared to sedentary rats  (P<0.05). In conclusion, the findings indicate that the low-intensity  exercise improves spatial learning and memory, as shown by  increased neuroplasticity and synaptic maturation in young Wistar  adult rats.
publisher: Journal of Exercise Physiologyonline
type: Article
type: PeerReviewed
format: text
language: en
identifier: http://repository.uhamka.ac.id/id/eprint/811/1/JEPonlineOCTOBER2018_Kartinah.pdf
identifier:   N. T. Kartinah, Kartinah dan Abdullah Faizah, Abdullah dan Aguspadita Diah Ayu, Diah dan Tahyatul Bariroh, Tahyatul   Low-Intensity Exercise Improves Neuroplasticity and Spatial Memory on Young Adult of Male Wistar Rats.  Low-Intensity Exercise Improves Neuroplasticity and Spatial Memory on Young Adult of Male Wistar Rats.