@article{repository787,
       publisher = {In Proceedings of BROMO Conference (BROMO 2018)},
           title = {Artocarpus altilis Leaves Activity in Inhibiting {\ensuremath{\alpha}}-Amylase Enzyme as Oral Antidiabetic Drug Candidate},
         journal = {Artocarpus altilis Leaves Activity in Inhibiting {\ensuremath{\alpha}}-Amylase Enzyme as Oral Antidiabetic Drug Candidate},
             url = {http://repository.uhamka.ac.id/id/eprint/787/},
        abstract = {Background: The search for effective antidiabetic drugs remains to be a focus of research in the world.
Artocarpus have been used as traditional medicine in South-East Asia. One of the species, Artocarpus altilis
has been known in Indonesia as traditional treatment for diabetic. Objective: This research aimed to
discover {\ensuremath{\alpha}}-amylase inhibitor activity of Artocarpus altilis leaves. Methods: Leaves were extracted by
maceration method, followed by phytochemical screening and quercetin identification using LC-MS
method. Inhibition of {\ensuremath{\alpha}}-amylase was measured using UV-Vis spectrophotometer at 524 nm wavelength,
while antioxidant activity was determined using DPPH. Results: Artocarpus altilis leaves ethanol extract
exhibited activity against {\ensuremath{\alpha}}-amylase with 155.96 ppm IC50 (0.27 times relative potential compared to
acarbose) and the extract showed antioxidant activity with the IC50 of 999.96 ppm. Conclusion: Artocarpus
altilis showed activity as the {\ensuremath{\alpha}}-amylase inhibitor.},
          author = {Lusi, Putri Dwita and Vivi Anggia, Vivi and Tri Dewi Prasetyatuti, Tri}
}