%0 Journal Article
%A H N Andjani, Andjani
%A Y Sentosa, Sentosa
%A YATI, KORI
%A A Fauzantoro, Fauzantoro
%A M Gozan, Gozan
%A Y J Yoo, Yoo
%A UHAMKA,
%F repository:745
%I IOP Publishing
%J IOP Conference Series: Earth and Environmental Science
%T Acute Oral Toxicity Test of Nicotiana tabacum L. Bio-Oil  Against Female Winstar Rats
%U http://repository.uhamka.ac.id/id/eprint/745/
%X Tobacco plants are notably known for its pesticidal properties, particularly due to its  nicotine content. In this study, Nicotiana tabacum L. bio-oil was obtained using pyrolysis  technique. The safety of the bio-oil to be used as bioinsecticide was analyzed through acute oral  toxicity test by administering 5000 mg bio-oil/kg body weight of female winstar rats that were  analogous to humans. It was concluded that the bio-oil was not toxic due to absence of mortality  and no significant change in the body weight and behavior of the rats.