@article{repository745, publisher = {IOP Publishing}, title = {Acute Oral Toxicity Test of Nicotiana tabacum L. Bio-Oil Against Female Winstar Rats}, journal = {IOP Conference Series: Earth and Environmental Science}, url = {http://repository.uhamka.ac.id/id/eprint/745/}, abstract = {Tobacco plants are notably known for its pesticidal properties, particularly due to its nicotine content. In this study, Nicotiana tabacum L. bio-oil was obtained using pyrolysis technique. The safety of the bio-oil to be used as bioinsecticide was analyzed through acute oral toxicity test by administering 5000 mg bio-oil/kg body weight of female winstar rats that were analogous to humans. It was concluded that the bio-oil was not toxic due to absence of mortality and no significant change in the body weight and behavior of the rats.}, author = {H N Andjani, Andjani and Y Sentosa, Sentosa and YATI, KORI and A Fauzantoro, Fauzantoro and M Gozan, Gozan and Y J Yoo, Yoo} }