%0 Journal Article
%@ 09751483, 09751505
%A Rini Prastiwi, Rini
%A UHAMKA,
%F repository:715
%I EManuscript Services
%J Journal Young Pharmacists
%T Antioxidant Activity of Rubus fraxinifolius Poir. and Rubus  rosifolius J. Sm. Leaves
%U http://repository.uhamka.ac.id/id/eprint/715/
%X Objective: Rubus fraxinifolius and R. rosifolius are found growing in  mountainous areas of West Java and potentially act as an antioxidant. The  objective of this research was to examine the antioxidant activity of Rubus  rosifolius J. Sm. and R. fraxinifolius Poir. leaves. Methods: Dried leaves  powder were extracted using Soxhlet apparatus with n-hexane, ethyl  acetate, and methanol. The extracts were evaporated, and antioxidant activity  was determined using DPPH free radical scavenger methods as well as  FRAP reduction capability. Total phenolic contents from the extract gave  the best antioxidant activity was measured by the Folin-Ciocalteu method.  Results: IC50 of DPPH scavenging activity of n-hexane, ethyl acetate and  methanolic extracts of R. fraxinifolius were >200; 140.97; and 4.48 ppm,  while for R. rosifolius were >200; 29.67; and 5.17 ppm, respectively.  Percent FRAP capacity of R. fraxinifolius in 25 ppm were 55.65; 89.47; and  97.65 %, while for R. rosifolius were 73.51; 82.83; and 96.5, respectively.  Total phenolic content of the methanolic extract of R. fraxinifolius and  R. rosifolius were 39.0 + 26.5 and 80.62+21.6 mg GAE/g extract.  Conclusion: Both methanolic extracts showed a significant optimum  trapping capability of free radicals and the hexane extracts did not show  antioxidant activity. Thus, it may be concluded that the methanolic extracts  of both leaves possess potent antioxidant properties and had high total  phenolic content. This investigation provides promising results to emphasize  the importance of antioxidant capabilities of both plants.