relation: http://repository.uhamka.ac.id/id/eprint/619/
title: Effect of Lecithin’s Concentration of Entrapment  Vitamin E Acetate Liposomes Using  Thin Layers Hydration Method
creator: Ari, Widayanti
creator: Rahmah, Elfiyani
creator: Dewi, Lestari
subject: H Social Sciences
description: Tocopheryl acetate is not oxidized and can penetrate through the skin to the living cells, where about 5% is  converted to free tocopherol and provides beneficial antioxidant effects. Lecithin is one of the main components  of liposomes vesicles forming. The higher the phospholipid used, the more vesicles are formed, so that drug  use is also expected to be optimal. This study aims to determine the effect of increased lecithin concentration  on the efficiency of vitamin E application in liposomes made by thin layer hydration method. In this study  3 formulas were prepared using cholesterol and lecithin with a ratio of 20 mg each:100 mg (F I), 20 mg:400 mg  (F II) and 20 mg:700 mg (F III). Evaluation of liposomes, among others, the efficiency of adsorption, particle  size and morphology. The results showed the formulation of vitamin E in liposome using thin layer hydration  method obtained liposomal adsorption efficiency from F I to F III, respectively that is 41,3799%; 47.6162% and  52.7216%. It can be concluded that an increase in lecithin concentration may increase the efficiency of the  adsorption in which F III is the best formula for improving the efficiency of adsorption.
publisher: American Scientific Publishers
type: Article
type: PeerReviewed
format: text
language: en
identifier: http://repository.uhamka.ac.id/id/eprint/619/1/Jurnal%20International%20%20ASL%20Ari%20Widayanti%20Desember%202017.pdf
identifier:   Ari, Widayanti dan Rahmah, Elfiyani dan Dewi, Lestari   Effect of Lecithin’s Concentration of Entrapment Vitamin E Acetate Liposomes Using Thin Layers Hydration Method.  Effect of Lecithin’s Concentration of Entrapment Vitamin E Acetate Liposomes Using Thin Layers Hydration Method.