@article{repository614, publisher = {Scientia Pharmaceutica}, journal = {The Anti-Inflammatory Activity of Nigella sativa Balm Sticks}, title = {The Anti-Inflammatory Activity of Nigella sativa Balm Sticks}, author = {Lusi, Putri Dwita and YATI, KORI and Sri, Nevi Gantini}, url = {https://www.mdpi.com/2218-0532/87/1/3?type=check\%5fupdate&version=1}, abstract = {Nigella sativa oil has been known to have potent anti-inflammatory activity. This research aimed to determine the anti-inflammation activity of Nigella sativa oil in a simple balm stick by topical application. The activity was checked using two methods: carrageenan-induced paw oedema and granuloma pouch on rats. The results showed that balm sticks which contained 10\% Nigella sativa could overcome both acute and sub-acute inflammation showing by high oedema inhibition (60.64\%), low leucocytes count (43.55\% lower than control) as well as a notable TNF-? concentration (50\% lower than control) on the inflamed area. In conclusion, topical application of a Nigella sativa balm stick was effective for both acute and sub-acute forms of inflammation.} }