<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Neuropharmacological activity of nut grass (Cyperus Rotundus L.) rhizome fraction"^^ . "The flavonoids content of Cyperus rotundus rhizomes is presumed to show activities on a central nervous system involving GABAergik. This research aimed to further investigate the neuropharmacological properties of Cyperus rotundus rhizomes fraction by measuring their hypnotic-sedative and anticonvulsant activities. The exploratory behavior test was performed using the hole-board method, while the motor coordination was assessed using the rotarod test. The results showed that the 70% ethanol fraction of Cyperus rotundus rhizome exhibited significant neuropharmacological activities (p < 0.05). Among the three fractions tested in this research (i.e., ethanol, ethyl acetate, and n-hexane), the ethanol fraction showed the best hypnotic-sedative and anticonvulsant activities. The ethanol fraction of Cyperus rotundus rhizome could shorten the duration of HLE equal to sodium valproate and potentiate phenobarbital-induced sleep by reducing the onset and prolonging the duration of sleep. The highest dose of the 70% ethanol fraction of Cyperus rotundus rhizome (356.7 mg/kg) displayed the best anxiolytic activity, resembling that of diazepam (p>0.05). In conclusion, Cyperus rotundus rhizome appeared as potent neuropharmacological drug candidate with abilities comparable to synthetic drugs."^^ . "2018" . . "8" . "2" . . "pharmaciana"^^ . . . "Pharmaciana"^^ . . . "20884559" . . . . . . . . . . . . . . . . . . . . . . "Sediarso"^^ . "Sediarso"^^ . "Sediarso Sediarso"^^ . . "Ladeska"^^ . "Vera"^^ . "Ladeska Vera"^^ . . "Adnan"^^ . "Adnan"^^ . "Adnan Adnan"^^ . . "Putri Dwita"^^ . "Lusi"^^ . "Putri Dwita Lusi"^^ . . "Wulan Sari"^^ . "Rahma"^^ . "Wulan Sari Rahma"^^ . . "Dewanti"^^ . "Ema"^^ . "Dewanti Ema"^^ . . "UHAMKA"^^ . . . . . . . "Neuropharmacological activity of nut grass (Cyperus Rotundus L.) rhizome fraction (Text)"^^ . . . "8938-29804-2-PB.pdf"^^ . . . "Neuropharmacological activity of nut grass (Cyperus Rotundus L.) rhizome fraction (Other)"^^ . . . . . . "indexcodes.txt"^^ . . . "Neuropharmacological activity of nut grass (Cyperus Rotundus L.) rhizome fraction (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Neuropharmacological activity of nut grass (Cyperus Rotundus L.) rhizome fraction (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Neuropharmacological activity of nut grass (Cyperus Rotundus L.) rhizome fraction (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Neuropharmacological activity of nut grass (Cyperus Rotundus L.) rhizome fraction (Other)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #602 \n\nNeuropharmacological activity of nut grass (Cyperus Rotundus L.) rhizome fraction\n\n" . "text/html" . . . "RS Pharmacy and materia medica"@en . .