eprintid: 5875
rev_number: 6
eprint_status: archive
userid: 2081
dir: disk0/00/00/58/75
datestamp: 2021-03-01 08:03:54
lastmod: 2021-03-01 08:03:54
status_changed: 2021-03-01 08:03:54
type: article
metadata_visibility: show
creators_name: Hikmawanti, Ni Putu
creators_name: Hanani, Endang
creators_id: ni.putu.ermi@uhamka.ac.id
creators_id: endang_hanani@uhamka.ac.id
creators_orcid: 0000-0001-5194-1431
title: Total Phenolic Content and Antioxidant Activity of Different Extracts of Cordia sebestena L. Leaves
ispublished: pub
subjects: H
divisions: 12
abstract: Background: Cordia sebestena L. (Boraginaceae) wildly planted in Jakarta, Indonesia. The secondary metabolites of plants have biological and pharmacological activities, such as antioxidant. The antioxidant activity of plants might be due to their phenolic compounds. Objective: To determine the total phenolic content and evaluate the antioxidant activity of C. sebestena leaves extracts (n-hexane, dichloromethane, ethyl acetate, and 70% ethanol).
Materials and Methods: The total phenolic content was determined using spectrophotometric methods with a Folin-Ciocalteu reagent. The antioxidant activity of the extracts was determined by its ability to inhibit DPPH radicals through IC50 values (ppm). Results: The highest total phenolic content (167.61 ± 0.56 mg GAE/g) and best antioxidant activity (31.41 ppm) were found in 70% ethanol extract of C. sebestena compared to other extracts (ethyl acetate > dichloromethane > n-hexane). Conclusion: The C. sebestena leaves have a good potential as a source of natural antioxidant, and further research, is recommended to evaluate the antioxidant activity using another method.
date: 2020-09-14
date_type: published
publisher: Pharmacognosy Network Worldwide
official_url: https://phcogj.com/article/1247
full_text_status: public
publication: Pharmacognosy Journal
volume: 12
number: 6
pagerange: 1311-1316
refereed: TRUE
issn: 0975-3575
related_url_url: https://phcogj.com/article/1247
citation:   Hikmawanti, Ni Putu dan Hanani, Endang  (2020) Total Phenolic Content and Antioxidant Activity of Different Extracts of Cordia sebestena L. Leaves.  Pharmacognosy Journal, 12 (6).  pp. 1311-1316.  ISSN 0975-3575     
document_url: http://repository.uhamka.ac.id/id/eprint/5875/1/Total%20Phenolic%20Content%20and%20Antioxidant%20Activity%20of%20Different.pdf