<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <http://repository.uhamka.ac.id/id/eprint/56429> .
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<http://repository.uhamka.ac.id/id/eprint/56429> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<http://repository.uhamka.ac.id/id/eprint/56429> <http://purl.org/dc/terms/title> "SKRIPSI-2210015037-RARA NADIKA-REPOSITORY"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://repository.uhamka.ac.id/id/eprint/56429> <http://purl.org/ontology/bibo/abstract> "Obesitas merupakan kondisi patologis yang ditandai oleh akumulasi jaringan adiposa berlebih\r\ndan dikaitkan dengan peningkatan produksi reactive oxygen species (ROS) yang\r\nmemicu stres oksidatif dan penurunan kadar glutathione (GSH). Holothuria atra merupakan\r\nspesies teripang yang mengandung senyawa bioaktif yang diduga mampu memodulasi\r\nkapasitas antioksidan endogen. Penelitian ini bertujuan untuk mengevaluasi efek pemberian\r\nekstrak H. atra terhadap kadar GSH aorta pada tikus obesitas yang diinduksi high\r\nfat diet (HFD). Penelitian eksperimental in vivo ini menggunakan tikus jantan Sprague\r\nDawley yang dibagi menjadi tiga kelompok: kelompok Pakan Normal, kelompok Pakan\r\nHFD, dan kelompok Pakan HFD+Ekstrak H. atra dengan dosis 300 mg/kgBB selama 6\r\nminggu. Kadar GSH aorta diukur menggunakan metode ELISA. Hasil penelitian menunjukkan\r\nbahwa kadar GSH aorta kelompok Pakan HFD+Ekstrak H. atra secara signifikan\r\nlebih tinggi dibandingkan kelompok Pakan HFD (3,36 ± 0,15 μg/mL vs 1,70 ± 0,02 μg/mL;\r\np < 0,001), meskipun belum mencapai kadar kelompok Pakan Normal (10,38 ± 1,08\r\nμg/mL). Temuan ini mengindikasikan bahwa ekstrak H. atra berpotensi meningkatkan kapasitas\r\nantioksidan endogen pada jaringan aorta tikus obesitas.\r\nKata kunci: glutathione, high fat diet, Holothuria atra, obesitas, Sprague Dawley"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://repository.uhamka.ac.id/id/eprint/56429> <http://purl.org/dc/terms/date> "2026" .
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<http://repository.uhamka.ac.id/id/document/300072> <http://eprints.org/relation/isVersionOf> <http://repository.uhamka.ac.id/id/document/300065> .
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<http://repository.uhamka.ac.id/id/eprint/56429/> <http://purl.org/dc/elements/1.1/title> "HTML Summary of #56429 \n\nSKRIPSI-2210015037-RARA NADIKA-REPOSITORY\n\n" .
<http://repository.uhamka.ac.id/id/eprint/56429/> <http://purl.org/dc/elements/1.1/format> "text/html" .
<http://repository.uhamka.ac.id/id/eprint/56429/> <http://xmlns.com/foaf/0.1/primaryTopic> <http://repository.uhamka.ac.id/id/eprint/56429> .
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<http://repository.uhamka.ac.id/id/subject/R> <http://www.w3.org/2004/02/skos/core#prefLabel> "R Medicine"@en .
<http://repository.uhamka.ac.id/id/eprint/56429> <http://purl.org/dc/terms/subject> <http://repository.uhamka.ac.id/id/subject/R> .
<http://repository.uhamka.ac.id/id/subject/Skripsi> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/02/skos/core#Concept> .
<http://repository.uhamka.ac.id/id/subject/Skripsi> <http://www.w3.org/2004/02/skos/core#prefLabel> "Skripsi" .
<http://repository.uhamka.ac.id/id/eprint/56429> <http://purl.org/dc/terms/subject> <http://repository.uhamka.ac.id/id/subject/Skripsi> .