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      "referencetext": "Abbas, Z. N., Al-Saffar, A. Z., Jasim, S. M., & Sulaiman, G. M. (2023).\r\nComparative study of colorectal cancer cell lines cultured in two- and threedimensional\r\nmodels: Insights into cellular morphologies, drug\r\nresponsiveness and transcriptomics. Research Square.\r\nhttps://doi.org/10.21203/rs.3.rs-2899480/v1\r\nAnanto, A. D., Muliasari, H., & Hamdin, C. D. (2020). Studi in silico bioaktivitas\r\nantikanker senyawa aktif dalam minyak biji buah wali [Brucea javanica (L.)\r\nMerr]. Sasambo Journal of Pharmacy, 1(2), 26\u201329.\r\nhttps://doi.org/10.29303/sjp.v1i2.13\r\nBabakhanova, G., Zimmerman, S. M., Pierce, L. T., Sarkar, S., Schaub, N. J., &\r\nSimon, C. G. (2022). Quantitative, traceable determination of cell viability\r\nusing absorbance microscopy. PLOS ONE, 17(1), e0262119.\r\nhttps://doi.org/10.1371/journal.pone.0262119\r\nBhanuwati, A. V., & Pakpahan, A. (2022). Cytotoxic test of different solvents of\r\nsoursop (Annona muricata) leaf extract against HSC-3 cell line. Dental\r\nJournal, 55(3), 130\u2013136. https://doi.org/10.20473/j.djmkg.v55.i3.p130-136\r\nBonsou, I. N., Mbaveng, A. T., Nguenang, G. S., Chi, G. F., Kuete, V., & Efferth,\r\nT. (2022). Cytotoxicity, acute and sub-chronic toxicities of the fruit extract\r\nof Tetrapleura tetraptera (Schumm. & Thonn.) Taub. (Fabaceae). BMC\r\nComplementary Medicine and Therapies, 22(1), Artikel 123.\r\nhttps://doi.org/10.1186/s12906-022-03659-1\r\nBrown, J. S., Amend, S. R., Austin, R. H., Gatenby, R. A., Hammarlund, E. U., &\r\nPienta, K. J. (2023). Updating the definition of cancer. Molecular Cancer\r\nResearch, 21(11), 1142\u20131147. https://doi.org/10.1158/1541-7786.MCR-\r\n23-0411\r\nChan, F., & Hamid, R. A. (2021). An overview of breast cancer: Classification and\r\nrelated signaling pathways. Progress in Drug Discovery & Biomedical\r\nScience. http://journals.hh-publisher.com/index.php/pmmb\r\nChoi, B. H., Kim, M. R., Jung, Y. N., Kang, S., & Hong, J. (2023). Interfering with\r\ncolor response by porphyrin-related compounds in the MTT tetrazoliumbased\r\ncolorimetric assay. Internasional Journal of Molecular Sciences,\r\n24(1), Artikel 562. https://doi.org/10.3390/ijms24010562\r\nCom\u015fa, \u015e., C\u00eempean, A. M., & Raica, M. (2015). The story of MCF-7 breast cancer\r\ncell line: 40 years of experience in research. Anticancer Research, 35(6),\r\n3147\u20133154.\r\nDjuwarno, E. N., Marhaba, Z., Abdullah, R., Baharuddin, R., Usuli, T. C., Ismail,\r\nN. H., & Tonde, N. A. (2023). Gambaran pengobatan pasca kemoterapi pasien kanker payudara pada rumah sakit di Provinsi Gorontalo. Jurnal\r\nMandala Pharmacon Indonesia, 9(2), 374\u2013382.\r\nhttps://doi.org/10.35311/jmpi.v9i2.328\r\nErber, R., & Hartmann, A. (2020). Histology of luminal breast cancer. Breast Care,\r\n15(4), 327\u2013336. https://doi.org/10.1159/000509025\r\nFarhan, M., Rizvi, A., Aatif, M., & Ahmad, A. (2023). Current understanding of\r\nflavonoids in cancer therapy and prevention. Metabolites, 13(4), Artikel\r\n481. https://doi.org/10.3390/metabo13040481\r\nFirdausi, I., & Retnowati, R. (2015). Fraksinasi ekstrak metanol daun mangga\r\nkasturi (Mangifera casturi Kosterm) dengan pelarut n-butanol. Jurnal Ilmu\r\nKimia Universitas Brawijaya, 1(1), 785\u2013790.\r\nhttps://www.neliti.com/publications/250050/\r\nFitriani, F., Subiwahjudi, A., Soetojo, A., & Yuanita, T. (2019). Sitotoksisitas\r\nekstrak kulit kakao (Theobroma cacao) terhadap kultur sel fibroblas BHK-\r\n21. Conservative Dentistry Journal, 9(1), 22\u201327.\r\nFitriasih, M. K. S., Sandra, F., Pratiwi, N., & Nisa Hidayati, D. (2019). Mangifera\r\nindica L. leaves extract induced intrinsic apoptotic pathway in MCF-7 cells\r\nby decreasing Bcl-2 expression and inducing Bax expression. Indonesian\r\nJournal of Cancer Chemoprevention, 10(2), 65\u201373.\r\nGhasemi, M., Turnbull, T., Sebastian, S., & Kempson, I. (2021). The MTT assay:\r\nUtility, limitations, pitfalls, and interpretation in bulk and single-cell\r\nanalysis. International Journal of Molecular Sciences, 22(23), Artikel\r\n12827. https://doi.org/10.3390/ijms222312827\r\nGovaerts, R., Nic Lughadha, E., Black, N., Turner, R., & Paton, A. (2021). The\r\nWorld Checklist of Vascular Plants, a continuously updated resource for\r\nexploring global plant diversity. Scientific Data, 8(1), Artikel 215.\r\nhttps://doi.org/10.1038/s41597-021-00997-6\r\nHolliday, D. L. (2011). Breast cancer research: bcr2889.\r\nHou, H. S., Lee, K. L., Tu, T. J., Cheng, J. Y., & Wei, P. K. (2025). Determination\r\nof half-maximal inhibitory concentration (IC50) of drugs using contrast\r\nsurface plasmon imaging on gold-coated periodic nanowires. Analytical\r\nChemistry, 97(38), 20817\u201320824.\r\nhttps://doi.org/10.1021/acs.analchem.5c02823\r\nKomariyah, M. S., Sandra, F., Pratiwi, N., & Hidayati, D. N. (2019). Mangifera\r\nindica L. leaves extract induced intrinsic apoptotic pathway in MCF-7 cells\r\nby decreasing Bcl-2 expression and inducing Bax expression. Indonesian\r\nJournal of Cancer Chemoprevention, 10(2), 65\u201373.\r\nKadhim Hassan, M., Fadhil Kadhim Jarallah, W., Nahid Thamer, Z., & Mohammed\r\nHussein, L. (2024). Gas chromatography-mass spectrometry (GC-MS)\r\nprinciple, instrument, detectors, and combining mass spectrometers with\r\nother techniques. Current Medical Research and Opinion, 7(6), 2634\u20132645.\r\nhttps://doi.org/10.52845/cmro/2024/7-6-27\r\nKEGG. (2018). KEGG PATHWAY: Breast cancer \u2013 Reference pathway.\r\nhttps://www.kegg.jp/pathway/map05224\r\nKhairunnisa Hero, S., & Cholil, A. (2021). Faktor risiko kanker payudara. Jurnal\r\nMedika Hutama, 3(1), 1533\u20131537.\r\nhttps://jurnalmedikahutama.com/index.php/JMH/article/view/310\r\nKong, X., Liu, Z., Cheng, R., Sun, L., Huang, S., Fang, Y., & Wang, J. (2020).\r\nVariation in breast cancer subtype incidence and distribution by\r\nrace/ethnicity in the United States from 2010 to 2015. JAMA Network Open,\r\n3(10), e2020303. https://doi.org/10.1001/jamanetworkopen.2020.20303\r\nKumar, M., Saurabh, V., Tomar, M., Hasan, M., Changan, S., Sasi, M.,\r\nMaheshwari, C., Prajapati, U., Singh, S., Prajapat, R. K., Dhumal, S., Punia,\r\nS., Amarowicz, R., & Mekhemar, M. (2021). Mango (Mangifera indica L.)\r\nleaves: Nutritional composition, phytochemical profile, and healthpromoting\r\nbioactivities. Antioxidants, 10(2), Artikel 299.\r\nhttps://doi.org/10.3390/antioxidants10020299\r\nKumar, V., Abbas, A. K., Aster, J. C., & Perkins, J. A. (2018). Robbins basic\r\npathology (10th ed.). Elsevier.\r\nLelwala, E. I., Seamasinghe, W. M., & Gunarathna, K. M. L. M. (2024).\r\nNonparametric approach to detecting seasonality in time series: Application\r\nof the Kruskal-Wallis (KW) test on tourist arrivals to Sri Lanka. South Asian\r\nJournal of Business Insights, 4(1), 3\u201319.\r\nhttps://doi.org/10.4038/sajbi.v4i1.61\r\nLem, F. F., Cheong, B. E., & Teoh, P. L. (2022). Ruellia tuberosa ethyl acetate leaf\r\nextract induces apoptosis and cell cycle arrest in human breast cancer cell\r\nline, MCF-7. Scientia Pharmaceutica, 90(3), Artikel 44.\r\nhttps://doi.org/10.3390/scipharm90030044\r\n\u0141ukasiewicz, S., Czeczelewski, M., Forma, A., Baj, J., Sitarz, R., & Stanis\u0142awek,\r\nA. (2021). Breast cancer\u2014Epidemiology, risk factors, classification,\r\nprognostic markers, and current treatment strategies\u2014An updated review.\r\nCancers, 13(17), Artikel 4287. https://doi.org/10.3390/cancers13174287\r\nMadera, S., Chervo, M. F., Chiauzzi, V. A., Pereyra, M. G., Venturutti, L., Izzo, F.,\r\nRold\u00e1n Deamicis, A., Guzman, P., Dupont, A., Roa, J. C., Cenciarini, M.\r\nE., Barchuk, S., Figurelli, S., Lopez Della Vecchia, D., Levit, C.,\r\nLebersztein, G., Anfuso, F., Castiglioni, T., Cortese, E., \u2026 Elizalde, P. V. (2020). Nuclear PDCD4 expression defines a subset of luminal B-like breast\r\ncancers with good prognosis. Hormones and Cancer, 11(5\u20136), 218\u2013239.\r\nhttps://doi.org/10.1007/s12672-020-00392-4\r\nMahdiyah, L. L. Z. T., Muhtadi, A., & Hasanah, A. N. (2020). Teknik isolasi dan\r\npenentuan struktur mangiferin: Senyawa aktif dari tanaman mangga\r\n(Mangifera indica L.). Majalah Farmasetika, 5(4), 167\u2013179.\r\nhttps://doi.org/10.24198/mfarmasetika.v5i4.27238\r\nMauro-Lizcano, M., Sotgia, F., & Lisanti, M. P. (2022). Ribosomal proteins as\r\nbiomarkers of age and cancer progression. Aging, 14(22), 9877.\r\nwww.aging-us.com\r\nMasota, N. E., Vogg, G., Heller, E., & Holzgrabe, U. (2020). Comparison of\r\nextraction efficiency and selectivity between low-temperature pressurized\r\nmicrowave-assisted extraction and prolonged maceration. Archiv der\r\nPharmazie, 353(10), Artikel 2000147.\r\nhttps://doi.org/10.1002/ardp.2000147\r\nMei, S., Ma, H., & Chen, X. (2021). Anticancer and anti-inflammatory properties\r\nof mangiferin: A review of its molecular mechanisms. Food and Chemical\r\nToxicology, 149, Artikel 111997. https://doi.org/10.1016/j.fct.2021.111997\r\nMoon, H. R., Ospina-Mu\u00f1oz, N., Noe-Kim, V., Yang, Y., Elzey, B. D., Konieczny,\r\nS. F., & Han, B. (2020). Subtype-specific characterization of breast cancer\r\ninvasion using a microfluidic tumor platform. PLoS ONE, 15(6), e0234012.\r\nhttps://doi.org/10.1371/journal.pone.0234012\r\nNoviyanty, Y., & Ardelia, W. (2022). Penetapan kadar senyawa flavonoid total dari\r\nekstrak etanol kulit buah mangga arum manis (Mangifera indica L. var.\r\nArum Manis) dengan metode spektrofotometri UV-Vis. Jurnal Sains\r\nKesehatan, 29(1), 34\u201342.\r\nPadma Sari, Y., Santoso, U., Junjung Nindhiani, F., Romadhan, P., & Kusuma Tuti,\r\nH. (2026). Identifikasi komposisi kimia asap cair tandan kosong kelapa\r\nsawit (TKKS) dan kajian literatur potensi insektisidanya. Dinamika\r\nPertanian, 41(1). https://journal.uir.ac.id/index.php/dinamikapertanian\r\nPeng, S., Li, Y., Huang, M., Tang, G., Xie, Y., Chen, D., Hu, Y., Yu, T., Cai, J.,\r\nYuan, Z., Wang, H., Wang, H., Luo, Y., & Liu, X. (2022). Metabolomics\r\nreveals that CAF-derived lipids promote colorectal cancer peritoneal\r\nmetastasis by enhancing membrane fluidity. International Journal of\r\nBiological Sciences, 18(5), 1912\u20131932. https://doi.org/10.7150/ijbs.68484\r\nPradani, M., Ponco Rahayu, M., Harjanti, R., & Priya Haresmita, P. (2024). Profil\r\nekstrak rimpang lengkuas (Alpinia galanga (L.) Willd.) dari lokasi tanam\r\ndengan perbedaan letak ketinggian geografis. PHARMACY: Jurnal Farmasi\r\nIndonesia, 21(1). https://jurnalnasional.ump.ac.id/index.php/PHARMACY\r\nRahman, W., & Barstow, M. (2023). Mangifera sumbawaensis. The IUCN Red List\r\nof Threatened Species. https://doi.org/10.2305/IUCN.UK.2023-\r\n1.RLTS.T32062A61526933.EN\r\nRawal, P., Baral, R., & Panta, S. (2025). In vitro experimental study of aqueous and\r\nethanolic extracts of selected medicinal plants for free radical scavenging\r\nand hypoglycemic activity. Current Perspectives on Medicinal and\r\nAromatic Plants, 8(2), 36\u201350. https://doi.org/10.38093/cupmap.1728419\r\nRiss, T. L., Moravec, R. A., Niles, A. L., Duellman, S., Benink, H. A., Worzella,\r\nT. J., & Minor, L. (2016). Cell viability assays. Dalam Assay Guidance\r\nManual. NCBI. https://www.ncbi.nlm.nih.gov/sites/books/NBK144065/\r\nSuryanto, E., & Wehantouw, D. F. (2009). Aktivitas penangkap radikal bebas dari\r\nekstrak fenolik daun sukun (Artocarpus altilis F.). Chemistry Progress, 2(2),\r\n77\u201383.\r\nSyafriana, V., & Puspitasari, L. (2024). Total flavonoid dan aktivitas antibakteri\r\ninfusa daun sempur (Dillenia suffruticosa (Griff. Ex Hook f. & Thomson)\r\nMartelli). Berita Biologi, 23(2), 207\u2013214.\r\nhttps://doi.org/10.55981/beritabiologi.2024.3257\r\nSayuti, M. (2017). Pengaruh perbedaan metode ekstraksi bagian dan jenis pelarut\r\nterhadap rendemen dan aktifitas antioksidan bambu laut (Isis hippuris).\r\nJurnal Teknologi Kimia Unimal, 6(1), 14\u201323.\r\nSegeritz, C. P., & Vallier, L. (2017). Cell culture: Growing cells as model systems\r\nin vitro. Dalam Basic Science Methods for Clinical Researchers (pp. 151\u2013\r\n172). Elsevier Inc. https://doi.org/10.1016/B978-0-12-803077-6.00009-6\r\nSinn, H. P., & Kreipe, H. (2013). A brief overview of the WHO classification of\r\nbreast tumors, 4th edition, focusing on issues and updates from the 3rd\r\nedition. Breast Care, 8(2), 149\u2013154. https://doi.org/10.1159/000350774\r\nSivakumaran, N., Samarakoon, S. R., Adhikari, A., Ediriweera, M. K., Tennekoon,\r\nK. H., Malavige, N., Thabrew, I., & Shrestha, R. L. S. (2018). Cytotoxic\r\nand apoptotic effects of govaniadine isolated from Corydalis govaniana\r\nWall. Roots on human breast cancer (MCF-7) cells. BioMed Research\r\nInternational, 2018, Artikel 3171348.\r\nhttps://doi.org/10.1155/2018/3171348\r\nStujanna, E. N., Ningsih, S. S., Nurusshofa, Z., Putri, N. D., Yashiro, T., & Sukarya,\r\nW. S. (2024). Affordable and simple protocol for immunofluorescence\r\nstaining of insulin secreting iGL cell line 2D and 3D. Journal of\r\nExperimental and Clinical Medicine, 41(3), 590\u2013594.\r\nhttps://doi.org/10.52142/omujecm.41.3.24\r\nTan, X. J., Cheor, W. L., Cheng, E. M., Ab Rahman, K. S., Wan Muhamad, W. Z.\r\nA., & Leow, W. Z. (2023). Breast cancer status, grading system, etiology,\r\nand challenges in Asia: An updated review. Oncologie, 25(2), 99\u2013110.\r\nhttps://doi.org/10.1515/oncologie-2022-1011\r\nTine, Y., Yang, Y., Renucci, F., Costa, J., W\u00e9l\u00e9, A., & Paolini, J. (2017). LCMS/\r\nMS analysis of flavonoid compounds from Zanthoxylum\r\nzanthoxyloides extracts and their antioxidant activities. Natural Product\r\nCommunications, 12(12), 1865\u20131868.\r\nhttps://doi.org/10.1177/1934578x1701201213\r\nUhrig, M., Ezquer, F., & Ezquer, M. (2022). Improving cell recovery: Freezing and\r\nthawing optimization of induced pluripotent stem cells. Cells, 11(5), Artikel\r\n799. https://doi.org/10.3390/cells11050799\r\nWahyuningsih, S., Yunita, I., Utari Yolla Sundari, M., Devi Bunga Pagalla, M.,\r\nYolan Kalalinggi, S., Alpian, M., Enny Nurmalasari, M., Hendy\r\nSuryandani, M., Ramlah, M., & Yolla Sundari, U. (2024). Ekstraksi bahan\r\nalam. Gita Lentera. https://gitalentera.com\r\nWen, Y., Chen, Z., Lu, J., Ables, E., Scemama, J. L., Yang, L. V., Lu, J. Q., & Hu,\r\nX. H. (2017). Quantitative analysis and comparison of 3D morphology\r\nbetween viable and apoptotic MCF-7 breast cancer cells and\r\ncharacterization of nuclear fragmentation. PLoS ONE, 12(9), e0184726.\r\nhttps://doi.org/10.1371/journal.pone.0184726\r\nWilkinson, A. N. (2023). Demystifying breast cancer. Canadian Family Physician,\r\n69(7), 473\u2013476. https://doi.org/10.46747/cfp.6907473\r\nWu, S. Z., Roden, D. L., Al-Eryani, G., Bartonicek, N., Harvey, K., Cazet, A. S.,\r\nChan, C. L., Junankar, S., Hui, M. N., Millar, E. A., Beretov, J., Horvath,\r\nL., Joshua, A. M., Stricker, P., Wilmott, J. S., Quek, C., Long, G. V.,\r\nScolyer, R. A., Yeung, B. Z., \u2026 Swarbrick, A. (2021). Cryopreservation of\r\nhuman cancers conserves tumour heterogeneity for single-cell multi-omics\r\nanalysis. Genome Medicine, 13(1), Artikel 81.\r\nhttps://doi.org/10.1186/s13073-021-00885-z\r\nYuliana, D. (2024). Literature review: Perkembangan pengobatan kemoterapi\r\nkanker payudara. Makassar Pharmaceutical Science Journal, 2(1), 2024\u2013\r\n2056. https://journal.farmasi.umi.ac.id/index.php/mpsj\r\nZaini, M., Hidriya, H., & Japeri, J. (2020). Aktivitas antioksidan ekstrak etanol\r\nMuntingia calabura dengan variasi laju pengadukan menggunakan\r\nmacerator-magnetic stirrer (M-MS). Jurnal Pharmascience, 7(2), 27\u201335.\r\nhttps://ppjp.ulm.ac.id/journal/index.php/pharmascience\r\nZakaria, F., Talip, B. A., Kahar, E. E. M., Muhammad, N., Abdullah, N., & Basri,\r\nH. (2020). Solvent used in extraction process of agarwood: A systematic review. Food Research, 4(3), 731\u2013737.\r\nhttps://doi.org/10.26656/fr.2017.4(3).333\r\nZhang, P., Liu, H., Yu, Y., Peng, S., Zeng, A., & Song, L. (2025). Terpenoids\r\nmediated cell apoptosis in cervical cancer: Mechanisms, advances and\r\nprospects. Fitoterapia, 180, Artikel 106323.\r\nhttps://doi.org/10.1016/j.fitote.2024.106323\r\nZhao, L., Shang, S., Tian, Y., Gao, Y., Song, Z., Peng, L., Li, Z., & Wang, B.\r\n(2023). Integrative analysis of sensory evaluation and non-targeted\r\nmetabolomics to unravel tobacco leaf metabolites associated with sensory\r\nquality of heated tobacco. Frontiers in Plant Science, 14, Artikel 1123100.\r\nhttps://doi.org/10.3389/fpls.2023.1123100\r\nZulkarnain, R. C., & Delyuzar. (2017). Karakteristik penderita kanker payudara di\r\nLaboratorium Patologi Anatomi Rumah Sakit Umum Pusat H. Adam Malik\r\nMedan. Jurnal Kedokteran Ibnu Nafis, 6(2).",
      "institution": "Universitas Muhammadiyah Prof. DR. Hamka",
      "abstract": "Eksplorasi agen sitotoksik bahan alam diperlukan untuk mengatasi efek samping dari terapi\r\nkonvensional yang sudah ada pada kanker payudara subtipe Luminal A. Penelitian in vitro\r\nini bertujuan mengevaluasi efek ekstrak metanol daun Mangifera sumbawaensis terhadap\r\nviabilitas dan morfologi sel kanker payudara MCF-7. Komponen bioaktif diekstraksi\r\nmelalui maserasi metanol, lalu diidentifikasi menggunakan Gas Chromatography-Mass\r\nSpectrometry (GC-MS). Uji sitotoksik selanjutnya dilakukan via MTT assay pada\r\nkonsentrasi 62,5\u20131000 ppm dengan inkubasi selama 24 jam. Analisis data menggunakan\r\nOne-Way ANOVA dan regresi linear untuk menentukan nilai IC!\". Hasil GC-MS\r\nmenunjukkan profil metabolit didominasi ester asam lemak dengan Methyl cis-13-\r\noctadecenoate (20,37%) sebagai komponen utama. Secara mikroskopis, paparan ekstrak\r\nmemicu perubahan morfologi berupa sel membulat, pengerutan sitoplasma, dan serpihan\r\napoptosis pada konsentrasi 500 dan 1000 ppm. Walaupun perlakuan ekstrak Mangifera\r\npada konsentrasi 1000 ppm mampu menurunkan viabilitas sel hingga 47,15%, tren\r\npenurunan tersebut secara statistik tidak menunjukkan perbedaan yang signifikan (p =\r\n0,1044). Perhitungan regresi linear menunjukkan estimasi nilai IC!\" sebesar 947,152 ppm.\r\nHal ini menunjukkan bahwa ekstrak metanol daun Mangifera sumbawaensis memiliki\r\naktivitas sitotoksik yang lemah, namun tetap berpotensi memicu apoptosis pada konsentrasi\r\ntinggi.\r\nKata Kunci: Mangifera sumbawaensis, MCF-7, MTT assay, Sitotoksisitas Lemah.",
      "ispublished": "pub",
      "thesis_name": "bphil",
      "creators": [
        {
          "name": {
            "honourific": null,
            "lineage": null,
            "given": "FATIH",
            "family": "FATIH ABDURRAHMAN A"
          }
        }
      ],
      "full_text_status": "restricted",
      "title": "SKRIPSI-2210015031-FATIH ABDURRAHMAN A-REPOSITORY",
      "datestamp": "2026-09-14 09:02:13",
      "rev_number": 8,
      "divisions": [
        11201
      ],
      "eprintid": 56382
    }