<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Simultaneous Analysis of 6-Mercaptopurine,\r\n6-Methylmercaptopurine, and 6-Thioguanosine-5’-monophosphate in Dried Blood Spot\r\nUsing Ultra Performance Liquid Chromatography Tandem Mass Spectrometry"^^ . "6-Mercaptopurine is a chemotherapeutic agent of the antimetabolite class. This study aims to analyze\r\nsimultaneous validation of 6-mercaptopurine (6-MP), 6-methylmercaptopurine (6-MMP), and 6-thioguanosine-5’-\r\nmonophosphate (6-TGMP) in dried blood spot (DBS) using ultra performance liquid chromatography-tandem mass\r\nspectrometry (UPLC-MS/MS). An accurate volume of 60 μL blood was spotted onto DBS-CAMAG paper and then\r\nextracted using methanol 90% (v/v) containing an internal standard of 5-fluorouracil (5-FU). Separation was\r\nperformed using a Waters Acquity UPLC BEH AMIDA column 1.7 μm (2.1 x 100 mm) with a mobile phase mixture of\r\n0.2% (v/v) formic acid in water−0.1% (v/v) formic acid in acetonitrile-methanol with gradient elution and flow rate of\r\n0.2 mL/min. Mass detection was done using Waters Xevo TQD with positive electrospray ionization (ESI) for 6-MP,\r\n6-MMP, 6-TGMP and negative ESI for 5-FU, in multiple reaction monitoring mode. Detection rates of 6-MP, 6-MMP,\r\n6-TGMP and 5-FU were m/z 153.09 > 119.09; 167.17 > 126.03; 380.16 > 168.00); 129.09 > 42.05, respectively. This\r\nmethod is linear across the range of 25.5–1020 ng/mL for 6-MP, 6-MMP and 6-TGMP. This method is valid for the in\r\nvitro simultaneous analysis of 6-MP, 6-MMP and 6-TGMP in DBS, based on European Medicine Agency guidelines."^^ . . . "544" . "551" . . "Indochem"^^ . . . . . . . . "Supandi"^^ . "Supandi Supandi"^^ . "Supandi Supandi Supandi"^^ . . . . . . "Simultaneous Analysis of 6-Mercaptopurine,\r\n6-Methylmercaptopurine, and 6-Thioguanosine-5’-monophosphate in Dried Blood Spot\r\nUsing Ultra Performance Liquid Chromatography Tandem Mass Spectrometry (Text)"^^ . . . "IJC-2018.pdf"^^ . . . "Simultaneous Analysis of 6-Mercaptopurine,\r\n6-Methylmercaptopurine, and 6-Thioguanosine-5’-monophosphate in Dried Blood Spot\r\nUsing Ultra Performance Liquid Chromatography Tandem Mass Spectrometry (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Simultaneous Analysis of 6-Mercaptopurine,\r\n6-Methylmercaptopurine, and 6-Thioguanosine-5’-monophosphate in Dried Blood Spot\r\nUsing Ultra Performance Liquid Chromatography Tandem Mass Spectrometry (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Simultaneous Analysis of 6-Mercaptopurine,\r\n6-Methylmercaptopurine, and 6-Thioguanosine-5’-monophosphate in Dried Blood Spot\r\nUsing Ultra Performance Liquid Chromatography Tandem Mass Spectrometry (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Simultaneous Analysis of 6-Mercaptopurine,\r\n6-Methylmercaptopurine, and 6-Thioguanosine-5’-monophosphate in Dried Blood Spot\r\nUsing Ultra Performance Liquid Chromatography Tandem Mass Spectrometry (Other)"^^ . . . . . . "small.jpg"^^ . . . "Simultaneous Analysis of 6-Mercaptopurine,\r\n6-Methylmercaptopurine, and 6-Thioguanosine-5’-monophosphate in Dried Blood Spot\r\nUsing Ultra Performance Liquid Chromatography Tandem Mass Spectrometry (Other)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #547 \n\nSimultaneous Analysis of 6-Mercaptopurine, \n6-Methylmercaptopurine, and 6-Thioguanosine-5’-monophosphate in Dried Blood Spot \nUsing Ultra Performance Liquid Chromatography Tandem Mass Spectrometry\n\n" . "text/html" . . . "R Medicine (General)"@en . .