@article{repository5070, title = {SUBCHRONIC TOXICITY TEST OF COMBINATION OF GINGER (Zingiber officinale Rosc.) EXTRACT AND ZINC ON SWISS WEBSTER MICE}, journal = {Proceding International Seminar FFS UHAMKA}, publisher = {Fakultas Farmasi dan Sains Universitas Muhammadiyah Prof. Dr. Hamka}, year = {2015}, pages = {157--164}, month = {January}, abstract = {The combination of ginger (Zingiber officinale Rosc.) extract and zinc has the effect of lowering levels of glucose. triglycerides. cholesterol and anti-oxidants. This study aimed to determine the safety administration of combination ginger extract and zinc. through the subchronic toxicity test. Parameters measured were body weight. liver and kidney histopathology. SGOT. and SGPT. The study used a sample of 20 male mice. divided into one control group and one treatment group. The extract was given orally through a sonde for 75 days. The treatment group was given a combination of ginger extract and zinc (ginger 30mg / 20g BW + zinc 0.4mg / 20g BW ) and the control group was given water. After 75 days of treatment sample blood the heart and then checked SGOT and SGPT. The collected statistical results with the method of independent samples T-test showed no significant difference between the levels of SGOT and SGPT control group to the treatment group. It can be concluded the combination of ginger extract and zinc did not show any toxic effects in subchronic and did not cause toxicity and damage to vital organs, such as liver and kidney}, issn = {978-602-71959-0-5}, url = {http://repository.uhamka.ac.id/id/eprint/5070/}, author = {Siska, Siska} }