relation: http://repository.uhamka.ac.id/id/eprint/5058/
title: ALPHA-GLUCOSIDASE INHIBITORY ACTIVITY OF ENDOPHYTIC BACTERIA  METABOLITES OF DAUN SALAM (Syzygium polyanthum (Wight) Walp.)
creator: Siska, Siska
subject: Q Science (General)
description: Diabetes mellitus is a metabolic disease associated with abnormally high level of the sugar glucose in the  blood. One of the treatment to lower the level of blood sugar is using the drug which inhibit the activity  of α-glucosidase. Daun salam (Syzygium polyanthum (Wight) Walp.) also known as bay leaves is a medicinal plant  contains active compound which showed α-glucosidase inhibitory activity. As every vascular plant  contains endophytic bacteria, the purpose of this study was to determine the alpha-glucosidase inhibitory  activity of endophytic bacteria’s metabolites of bay leaves. Isolation of endophytic bacteria was conducted  using direct plating method of bay leaves using NA medium. The obtained bacterial isolates then cultivated in a  liquid F4 medium, incubated for 5 days, and harvested by centrifugation to obtain endophyte’s metabolites.  The supernatant was used for enzyme inhibitory assay using p-nitrophenyl-Alpha-D-glucopyranose (p-NPG) as  a substrate. Results showed that the alpha-glucosidase inhibitory activity of the metabolites of 5 endophytic  bacteria isolates was 37.67%; 37.77%; 36.21; 45.81%; and 41.90%. respectively. It can be concluded that the  metabolites of endophytic bacteria of bay leaves have alpha-glucosidase inhibitory activity.
publisher: Fakultas Farmasi dan Sains Universitas Muhammadiyah Prof. Dr. Hamka
date: 2016-08
type: Article
type: PeerReviewed
format: text
language: en
identifier: http://repository.uhamka.ac.id/id/eprint/5058/1/17.pdf
format: text
language: en
identifier: http://repository.uhamka.ac.id/id/eprint/5058/3/ALPHA-GLUCOSIDASE%20INHIBITORY%20ACTIVITY%20OF%20ENDOPHYTIC%20BACTERIA%20METABOLITES%20OF%20DAUN%20SALAM%20%28Syzygium%20polyanthum%20%28Wight%29%20Walp.%29.pdf
format: text
language: en
identifier: http://repository.uhamka.ac.id/id/eprint/5058/19/17.%20PR%20Prosiding%20FFS_Alpha%202016.pdf
identifier:   Siska, Siska  (2016) ALPHA-GLUCOSIDASE INHIBITORY ACTIVITY OF ENDOPHYTIC BACTERIA METABOLITES OF DAUN SALAM (Syzygium polyanthum (Wight) Walp.).  Prosiding Internasional Seminar.   ISSN 978-602-71959-2-9