relation: http://repository.uhamka.ac.id/id/eprint/48479/
title: Evaluation of analgesic and anti-inflammatory activities of  ethanolic extract of Cordia sebestena L.
creator: Hadi Sunaryo, Hadi
creator: Siska, Siska
subject: Fakultas Farmasi dan Sains
description: Trees and shrubs of the genus Cordia are widely distributed in the warmer regions, including Indonesia. The aim of this study  was to evaluate the analgesic and anti-inflammatory properties of the ethanolic extract of plant leaves in Wistar albino rats.  The analgesic activity was evaluated using the hot plate method and acetic acid-induced writhing, and the anti-inflammatory  activity was determined using carrageenan-induced paw oedema. The results showed that the Cordia sebestena ethanol extract  (100, 200 and 400 mg/kg) exhibited significant analgesic effects in a dose-dependent manner in the two pain models tested. The  extract also exhibited significant anti-inflammatory effects in the carrageenan-induced inflammation test. The data obtained  support the traditional folklore therapeutic claim about its analgesic and anti-inflammatory properties. Nonetheless, further  scientific investigation is required to establish its analgesic and anti-inflammatory properties in other experimental models and  clinical settings.
type: Article
type: PeerReviewed
format: text
language: en
identifier: http://repository.uhamka.ac.id/id/eprint/48479/1/European%20Pharmaceutical%20Journal%20Evaluation%20of%20analgesic%20and%20anti-inflammatory%20activities%20of%20ethanolic%20extract%20of%20Cordia%20sebestena%20L..pdf
identifier:   Hadi Sunaryo, Hadi dan Siska, Siska   Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L.  EUROPEAN PHARMACEUTICAL JOURNAL.