<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Docking Studies and Molecular Dynamics Simulation of Ipomoea batatas\r\nL. Leaves Compounds as Lipoxygenase (LOX) Inhibitor"^^ . "Inflammatory mediators produced by cyclooxygenase (COX) and\r\nlipoxygenase (LOX) pathways are responsible for many human diseases, such\r\nas cancer, arthritis, and neurological disorders. Flavonoid-containing plants,\r\nsuch as Ipomoea batatas leaves, have shown potential anti-inflammatory\r\nactivity. Objectives: This study aimed to predict the actions of 10 compounds\r\nin I. batatas leaves, which are YGM–0a [cyanidin 3–0–sophoroside–5–0–\r\nglucosede], YGM–0f [cyanidin 3–O–(2–0–(6–0–(E)–p–coumaroyl–β–D–\r\nglucopyranosyl)–β–D–glucopyranoside)–5–0–β–D–glucopyranoside],\r\nYGM–1a [cyanidin 3–(6,6′–caffeylp–hydroxybenzoylsophoroside) –5–\r\nglucoside], YGM–1b [cyanidin 3–(6,6′–dicaffeylsophor-oside)–5–glucoside],\r\nYGM–2 [cyanidin 3–(6–caffeylsophoroside)–5–glucoside], YGM–3 [cyanidin\r\n3–(6,6′–caffeyl-ferulylsophoroside)–5–glucoside], YGM–4b [peonidin 3–\r\n(6,6′–dicaffeylsophoroside)–5– glucoside], YGM–5a [peonidin 3–(6,6′–\r\ncaffeylphydroxybenzo-ylsophoroside)–5–gluco-side], YGM–5b [cyanidin\r\n3–6–caffeylsophoroside)–5–glucosede], and YGM–6 [peonidin 3–(6,6′–\r\ncaffeylferulylsophoroside)–5–glucoside] as LOX inhibitors, and also predict the\r\nstability of ligand–LOX complex. Materials and Methods: The compounds were\r\nscreened through docking studies using PLANTS. Also, the molecular dynamics\r\nsimulation was conducted using GROMACS at 310K. Results: The results\r\nshowed that the most significant binding affinity toward LOX was shown by\r\nYGM–0a and YGM–0a, and the LOX complex in molecular dynamics simulation\r\nshowed stability for 20 ns. Conclusion: Based on Docking Studies and Molecular\r\nDynamics Simulation of I. Batatas Leaves compounds, YGM-0a was shown to\r\nbe the most probable LOX inhibitor"^^ . "2020-11-05" . . "12" . "6" . . "Wolters Kluwer Medknow"^^ . . . "Docking Studies and Molecular Dynamics Simulation of Ipomoea batatas L. Leaves Compounds as Lipoxygenase (LOX) Inhibitor"^^ . . . . . . . . . . . . . . . . . . . . . ""^^ . ""^^ . " "^^ . . "Suswandari"^^ . "Suswandari"^^ . "Suswandari Suswandari"^^ . . "Yeni"^^ . "Yeni"^^ . "Yeni Yeni"^^ . . "Supandi"^^ . "Supandi Supandi"^^ . "Supandi Supandi Supandi"^^ . . "Lusi"^^ . "Lusi Putri Dwita"^^ . "Lusi Lusi Putri Dwita"^^ . . . . . . "Docking Studies and Molecular Dynamics Simulation of Ipomoea batatas\r\nL. Leaves Compounds as Lipoxygenase (LOX) Inhibitor (Text)"^^ . . . "JPharmBioallSci126836-2242964_061349.pdf"^^ . . . "Docking Studies and Molecular Dynamics Simulation of Ipomoea batatas\r\nL. Leaves Compounds as Lipoxygenase (LOX) Inhibitor (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Docking Studies and Molecular Dynamics Simulation of Ipomoea batatas\r\nL. Leaves Compounds as Lipoxygenase (LOX) Inhibitor (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Docking Studies and Molecular Dynamics Simulation of Ipomoea batatas\r\nL. Leaves Compounds as Lipoxygenase (LOX) Inhibitor (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Docking Studies and Molecular Dynamics Simulation of Ipomoea batatas\r\nL. Leaves Compounds as Lipoxygenase (LOX) Inhibitor (Other)"^^ . . . . . . "small.jpg"^^ . . . "Docking Studies and Molecular Dynamics Simulation of Ipomoea batatas\r\nL. Leaves Compounds as Lipoxygenase (LOX) Inhibitor (Other)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #4706 \n\nDocking Studies and Molecular Dynamics Simulation of Ipomoea batatas \nL. Leaves Compounds as Lipoxygenase (LOX) Inhibitor\n\n" . "text/html" . . . "Q Science (General)"@en . .