eprintid: 4703
rev_number: 52
eprint_status: archive
userid: 1558
dir: disk0/00/00/47/03
datestamp: 2020-11-15 14:20:10
lastmod: 2021-11-28 08:30:02
status_changed: 2021-11-28 08:30:02
type: article
metadata_visibility: show
creators_name: Siska, Siska
creators_id: siska@uhamka.ac.id
creators_orcid: 0000-0003-4830-9261
contributors_type: http://www.loc.gov/loc.terms/relators/AUT
contributors_type: http://www.loc.gov/loc.terms/relators/AUT
contributors_type: http://www.loc.gov/loc.terms/relators/AUT
contributors_name: Sunaryo, Hadi
contributors_name: Siska, Siska
contributors_name: Hanani, Endang
title: Evaluation of analgesic and anti-inflammatory activities of
ethanolic extract of Cordia sebestena L.
ispublished: pub
subjects: Q1
divisions: 12
abstract: Trees and shrubs of the genus Cordia are widely distributed in the warmer regions, including Indonesia. The aim of this study
was to evaluate the analgesic and anti-inflammatory properties of the ethanolic extract of plant leaves in Wistar albino rats.
The analgesic activity was evaluated using the hot plate method and acetic acid-induced writhing, and the anti-inflammatory
activity was determined using carrageenan-induced paw oedema. The results showed that the Cordia sebestena ethanol extract
(100, 200 and 400 mg/kg) exhibited significant analgesic effects in a dose-dependent manner in the two pain models tested. The
extract also exhibited significant anti-inflammatory effects in the carrageenan-induced inflammation test. The data obtained
support the traditional folklore therapeutic claim about its analgesic and anti-inflammatory properties. Nonetheless, further
scientific investigation is required to establish its analgesic and anti-inflammatory properties in other experimental models and
clinical settings.
date: 2019
publisher: Sciendo
official_url: https://content.sciendo.com/view/journals/afpuc/afpuc-overview.xml
full_text_status: public
publication: Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L.
volume: 66
number: 2
pagerange: 26-31
refereed: TRUE
issn: 1338-6786
citation:   Siska, Siska  (2019) Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L.  Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L., 66 (2).  pp. 26-31.  ISSN 1338-6786     
document_url: http://repository.uhamka.ac.id/id/eprint/4703/1/3.%20European_2019.pdf
document_url: http://repository.uhamka.ac.id/id/eprint/4703/4/European_2019_Evaluation%20of%20analgesic%20and%20anti-inflammatory%20activities%20of%20ethanolic%20extract%20of%20Cordia%20sebestena%20L..pdf
document_url: http://repository.uhamka.ac.id/id/eprint/4703/21/3.%20PR%20European%202019.pdf
document_url: http://repository.uhamka.ac.id/id/eprint/4703/22/3.%20Bukti%20korespondensi_European_2019.pdf