relation: http://repository.uhamka.ac.id/id/eprint/4703/ title: Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L. creator: Siska, Siska subject: Q Science (General) description: Trees and shrubs of the genus Cordia are widely distributed in the warmer regions, including Indonesia. The aim of this study was to evaluate the analgesic and anti-inflammatory properties of the ethanolic extract of plant leaves in Wistar albino rats. The analgesic activity was evaluated using the hot plate method and acetic acid-induced writhing, and the anti-inflammatory activity was determined using carrageenan-induced paw oedema. The results showed that the Cordia sebestena ethanol extract (100, 200 and 400 mg/kg) exhibited significant analgesic effects in a dose-dependent manner in the two pain models tested. The extract also exhibited significant anti-inflammatory effects in the carrageenan-induced inflammation test. The data obtained support the traditional folklore therapeutic claim about its analgesic and anti-inflammatory properties. Nonetheless, further scientific investigation is required to establish its analgesic and anti-inflammatory properties in other experimental models and clinical settings. publisher: Sciendo date: 2019 type: Article type: PeerReviewed format: text language: aa identifier: http://repository.uhamka.ac.id/id/eprint/4703/1/3.%20European_2019.pdf format: text language: en identifier: http://repository.uhamka.ac.id/id/eprint/4703/4/European_2019_Evaluation%20of%20analgesic%20and%20anti-inflammatory%20activities%20of%20ethanolic%20extract%20of%20Cordia%20sebestena%20L..pdf format: text language: en identifier: http://repository.uhamka.ac.id/id/eprint/4703/21/3.%20PR%20European%202019.pdf format: text language: en identifier: http://repository.uhamka.ac.id/id/eprint/4703/22/3.%20Bukti%20korespondensi_European_2019.pdf identifier: Siska, Siska (2019) Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L. Evaluation of analgesic and anti-inflammatory activities of ethanolic extract of Cordia sebestena L., 66 (2). pp. 26-31. ISSN 1338-6786 relation: https://content.sciendo.com/view/journals/afpuc/afpuc-overview.xml