eprintid: 41520
rev_number: 7
eprint_status: archive
userid: 2310
dir: disk0/00/04/15/20
datestamp: 2025-01-30 04:09:26
lastmod: 2025-01-30 04:09:26
status_changed: 2025-01-30 04:09:26
type: thesis
metadata_visibility: show
creators_name: Ni Putu, Ermi Hikmawati
creators_name: Agustin, Yumita
creators_id: ermy0907@uhamka.ac.id
creators_orcid: 0000-0001-5194-1431
title: UJI TOKSISITAS AWAL TIGA EKSTRAK BERBASIS KOLIN KLORIDA
DAUN BELUNTAS (Pluchea indica (L.) Less.) MENGGUNAKAN
METODE BRINE SHRIMP LETHALITY TEST (BSLT
ispublished: pub
subjects: RS
divisions: 48201
abstract: UJI TOKSISITAS AWAL TIGA EKSTRAK BERBASIS KOLIN KLORIDA
DAUN BELUNTAS (Pluchea indica (L.) Less.) MENGGUNAKAN
METODE BRINE SHRIMP LETHALITY TEST (BSLT)
Lathifah As’ad Dzulnia Sekar
1904015156
Beluntas (Pluchea indica (L.) Less.) merupakan tanaman yang mengandung
senyawa fenolik dan flavonoid. Penelitian sebelumnya menunjukkan bahwa
pelarut natural deep eutectic solvent (NADES) berbasis kolin klorida merupakan
pelarut alternatif berbahan alami yang relatif aman dan ramah lingkungan untuk
ekstraksi metabolit tanaman. Tujuan penelitian ini untuk mengetahui toksisitas
awal tiga pelarut dan ekstrak berbasis kolin klorida menggunakan metode Brine
Shrimp Lethality Test (BSLT) terhadap larve udang Artemia salina Leach (larva
udang). Pelarut NADES pada penelitian ini dibuat dari kolin klorida-urea (1:2),
kolin klorida-asam laktat (1:2), dan kolin klorida-1,3-butanediol (1:6) dengan
penambahan air 30% (v/v). Ekstraksi daun beluntas dengan NADES difasilitasi
dengan bantuan ultrasonik. Hasil penelitian menunjukkan semakin tinggi
konsentrasi ekstrak dan pelarut kolin klorida-urea (1:2), kolin klorida-asam laktat
(1:1), dan kolin klorida-1,3-butanediol (1:6) maka semakin tinggi persentase
kematian larva udang. Ekstrak dan pelarut kolin klorida-asam laktat (1:1) mampu
membunuh larva udang pada konsentrasi yang lebih rendah dibandingkan ekstrak
dan pelarut kolin klorida-urea (1:2) dan kolin klorida-1,3-butanediol (1:6).
Kata Kunci: Beluntas, NADES, Artemia salina Leach, BSLT, Fitokimia,
Toksisitas
date: 2024
date_type: completed
full_text_status: public
institution: UNIVERSITAS MUHAMMADIYAH PROF. DR. HAMKA
department: Fakultas Farmasi Dan Sains
thesis_type: bachelor
thesis_name: bphil
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citation:   Ni Putu, Ermi Hikmawati dan Agustin, Yumita  (2024) UJI TOKSISITAS AWAL TIGA EKSTRAK BERBASIS KOLIN KLORIDA DAUN BELUNTAS (Pluchea indica (L.) Less.) MENGGUNAKAN METODE BRINE SHRIMP LETHALITY TEST (BSLT.  Bachelor thesis, UNIVERSITAS MUHAMMADIYAH PROF. DR. HAMKA.   
document_url: http://repository.uhamka.ac.id/id/eprint/41520/1/FS03-240112.pdf