%X Stress can occur due to a person's inability to respond to a stressor, 
resulting in bodily or mental disorders. Anxiety can be 
characterized by increased levels of cortisol, which is regulated by 
the Hypothalamus-Pituitary-Adrenaline (HPA-axis). 
Aromatherapy is a therapy using essential oils that give a distinctive 
aroma to plant parts such as flowers, roots, leaves, and stems. 
Aromatherapy can be done through a reed diffuser. The frangipani 
(Plumeria alba) is one of the plants in Indonesia that has a particular 
scent in its flowers. This study aims to determine the effect of 
prolonged exposure to P. alba essential oil reed diffuser on cortisol 
levels in rats. Twenty-four rats were divided into four groups: the 
control group without exposure to a reed diffuser for 5 and 10 days 
and the other group with exposure for 5 and 10 days. Each blood 
was drawn through the retro-orbital, centrifuged to obtain serum, 
and tested using LC-MS to determine cortisol levels. The group with 
ten days of essential oil exposure showed lower cortisol levels. It 
can be concluded that the duration of aromatherapy exposure is 
connected to cortisol levels and that aromatherapy can be utilized 
as a stress-reduction therapy
%N 2
%A Siska Siska
%L repository33289
%D 2023
%P 120-124
%T The Effect of Long Exposure Reed Diffuser Essential Oil Plumeria alba
on Cortisol Levels of Male Wistar Rats
%V 6
%I Universitas Muhammadiyah Palangkaraya
%J The Effect of Long Exposure Reed Diffuser Essential Oil Plumeria alba on Cortisol Levels of Male Wistar Rats