eprintid: 31976 rev_number: 7 eprint_status: archive userid: 1610 dir: disk0/00/03/19/76 datestamp: 2024-02-02 01:20:15 lastmod: 2024-02-02 01:20:15 status_changed: 2024-02-02 01:20:15 type: article metadata_visibility: show creators_name: Fahjar Prisiska, Fahjar creators_id: fahjar.prisiska@uhamka.ac.id title: ICOPS IIUM-SURAT TUGAS-BUKTI PEMBAYARAN-SERTIFIKAT KEGIATAN-GENAP-2021-2022 ispublished: unpub subjects: C subjects: CC abstract: In the manufacture of tablets, the use of Polyvinylpyrrolidone (PVP) as a binder is common. PVP is a good binder for almost all types of tablets. In this study, PVP was tried to be used as a binder on tablets with the active ingredient of dry extract of red ginger added with zinc which is efficacious as an anti�atherosclerosis. The purpose of this study is to find out what is the optimum level of PVP as a binder that will produce physically qualified tablets, namely on hardness, brittleness, and time of disintegration. The experimental tablets were made in 5 formulas with a range of PVP binding concentration of 2.8% to 3.9%. Tablets are made by the wet granulation method, evaluated at the granulation stage and the tablet stage. The results showed that the granules for all the formulas made were qualified. The granule evaluation results which include moisture content and flow properties are all qualified to be pressed into tablets. The results of the tablet evaluation showed that of the five formulas tested for hardness, brittleness, and the time of disintegration met the conditions according to the reference used. If further observed from the data figures and based on the results of statistical tests it was obtained that the one with the best physical properties, namely the highest hardness with the fastest crushing time is in formula 5. Thus, it can be concluded that the optimal binding formula of PVP on ginger extract tablets with added zinc is 3.9% full_text_status: public publication: International Conference on Pharmaceutical Sciences ICOPS@IIUM2022 “Enhancement of Pharmacetical Efficacy Through Sustainable Research and Innovations” refereed: TRUE citation: Fahjar Prisiska, Fahjar ICOPS IIUM-SURAT TUGAS-BUKTI PEMBAYARAN-SERTIFIKAT KEGIATAN-GENAP-2021-2022. International Conference on Pharmaceutical Sciences ICOPS@IIUM2022 “Enhancement of Pharmacetical Efficacy Through Sustainable Research and Innovations”. (Unpublished) document_url: http://repository.uhamka.ac.id/id/eprint/31976/1/SURAT%20TUGAS-BUKTI%20PEMBAYARAN-BOOKS%20ABSTRAK-PPT-SERTIFIKAT%20ICOPS%20IIUM.pdf