<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "EFFECT OF INCREASING HPMC CONCENTRATION ON PARTICULATE\r\nDISSOLUTION OF SOLID DISPERSION SYSTEM KETOPROFEN-HPMC"^^ . "Ketoprofen is one of practically water insoluble drug compounds, the factor causing\r\ndissolution and bioavailability the drugs is very low. To dissolve this problem, a\r\nresearch was conducted by making solid dispersion system of ketoprofen using HPMC\r\nas hydrophilic polymer. The ketoprofen solid dispersion was made in 5 combination i.e.\r\n0%, 5%, 10%, 15%, and 20% of HPMC. Method of production of solid dispersion using\r\ndissolving method, with ethanol 70% as solvent. The solid dispersions were\r\ncharacterized for its crystal using thermal analyses by DSC (Differential Scanning\r\nCalorimetry), and followed for dissolution using paddle-type method in HCl pH 1.2\r\nbuffer as medium. The results showed that increasing of HPMC increased ED\r\n60\r\n of\r\nketoprofen, whiles the maximum value at 10% HPMC concentration with ED\r\n60\r\n 40.42%.\r\nBy one-way ANOVA analyses with 95% of significance level, among all combinations\r\nshowed a significant differences. On the other hand, thermal analyses results showed\r\nthat increasing of HPMC gave a slight decreasing melting point on solid dispersion\r\nsystem ketoprofen-HPMC below pure ketoprofen. It could be concluded that HPMC is\r\nless effective when used as a hydrophilic combination in solid dispersion."^^ . "2015-01-10" . . . "9786027195905" . . "FFS UHAMKA"^^ . . "FFS UHAMKA"^^ . . . . . . . . . . . . . . "Ani"^^ . "Ani Pahriyani"^^ . "Ani Ani Pahriyani"^^ . . "Gusmayadi"^^ . "Inding"^^ . "Gusmayadi Inding"^^ . . "Indriani"^^ . "Onny"^^ . "Indriani Onny"^^ . . . . . . "EFFECT OF INCREASING HPMC CONCENTRATION ON PARTICULATE\r\nDISSOLUTION OF SOLID DISPERSION SYSTEM KETOPROFEN-HPMC (Text)"^^ . . . "PROCEEDING Chalenges-ISBN 978-602-71959-0-5.pdf"^^ . . . "EFFECT OF INCREASING HPMC CONCENTRATION ON PARTICULATE\r\nDISSOLUTION OF SOLID DISPERSION SYSTEM KETOPROFEN-HPMC (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "EFFECT OF INCREASING HPMC CONCENTRATION ON PARTICULATE\r\nDISSOLUTION OF SOLID DISPERSION SYSTEM KETOPROFEN-HPMC (Other)"^^ . . . . . . "preview.jpg"^^ . . . "EFFECT OF INCREASING HPMC CONCENTRATION ON PARTICULATE\r\nDISSOLUTION OF SOLID DISPERSION SYSTEM KETOPROFEN-HPMC (Other)"^^ . . . . . . "medium.jpg"^^ . . . "EFFECT OF INCREASING HPMC CONCENTRATION ON PARTICULATE\r\nDISSOLUTION OF SOLID DISPERSION SYSTEM KETOPROFEN-HPMC (Other)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #23451 \n\nEFFECT OF INCREASING HPMC CONCENTRATION ON PARTICULATE \nDISSOLUTION OF SOLID DISPERSION SYSTEM KETOPROFEN-HPMC\n\n" . "text/html" . . . "Fakultas Farmasi dan Sains"@en . .