eprintid: 21281
rev_number: 8
eprint_status: archive
userid: 3858
dir: disk0/00/02/12/81
datestamp: 2023-02-17 07:43:41
lastmod: 2023-02-17 07:43:41
status_changed: 2023-02-17 07:43:41
type: thesis
metadata_visibility: show
creators_name: SURYANI, RIA
creators_name: Wahyudi, Priyo
creators_name: Hidayati, Wahyu
title: UJI AKTIVTAS EKSTRAK ETANOL 70% BIJI PINANG
(Areca catechu L.) TERHADAP PENGHAMBATAN PEMBENTUKAN
BIOFILM Pseudomonas aeruginosa
ispublished: pub
subjects: R
subjects: RS
divisions: 48201
abstract: Pseudomonas aeruginosa merupakan bakteri patogen Gram-negatif yang berperan
penting sebagai penyebab infeksi pada pasien luka bakar. Infeksi luka bakar yang
disebabkan oleh Pseudomonas aeruginosa memiliki karakteristik warna
kuning/hijau, berbau busuk, dan berlendir. Lapisan berlendir pada permukaan luka
bakar merupakan bentuk biofilm. Biofilm memberikan perlindungan pada sel
terhadap mekanisme pertahanan inang, fagositosis, dan pengobatan antibiotik. Biji
pinang mengandung senyawa flavonoid dan tanin yang memiliki aktivitas
menghambat pembentukan biofilm P.aeruginosa. Penelitian ini bertujuan untuk
menguji aktivitas ekstrak etanol 70% biji pinang (Areca catechu L.) terhadap
penghambatan pembentukan biofilm P.aeruginosa, menggunakan metode
microtitter plate assay, dan diwarnai dengan krisrtal violet 0,1%. Pengukuran
ditunjukan dari nilai absorbansi kristal violet yang diukur menggunakan microplate
reader pada panjang gelombang 595 nm. Berdasarkan penelitian yang dilakukan
dapat disimpulkan bahwa ekstrak etanol biji pinang (Areca catechu L.) mempunyai
aktivitas penghambatan pembentukan biofilm Pseudomonas aeruginosa dengan
nilai IC50 412,8573 µg/ml dan potensi relatif sebesar 0,2565 kali silver sulfadiazin.
Kata kunci: Areca catechu L., biji pinang, biofilm, Pseudomonas aeruginosa,
silver sulfadiazin
date: 2021
date_type: completed
full_text_status: public
institution: Universitas Muhammadiyah Prof. DR. HAMKA
department: Fakultas Farmasi dan Sains
thesis_type: bachelor
thesis_name: bphil
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citation:   SURYANI, RIA dan Wahyudi, Priyo dan Hidayati, Wahyu  (2021) UJI AKTIVTAS EKSTRAK ETANOL 70% BIJI PINANG (Areca catechu L.) TERHADAP PENGHAMBATAN PEMBENTUKAN BIOFILM Pseudomonas aeruginosa.  Bachelor thesis, Universitas Muhammadiyah Prof. DR. HAMKA.   
document_url: http://repository.uhamka.ac.id/id/eprint/21281/1/FS03-210369.pdf