eprintid: 20965
rev_number: 9
eprint_status: archive
userid: 3858
dir: disk0/00/02/09/65
datestamp: 2023-02-13 02:49:58
lastmod: 2023-02-13 02:49:58
status_changed: 2023-02-13 02:49:58
type: thesis
metadata_visibility: show
creators_name: Fitriani, Dhelia Nur
creators_name: Dwitiyanti, Dwitiyanti
creators_name: Hikmawanti, Ni Putu Ermi
title: JI AKTIVITAS FRAKSI-FRAKSI DAUN KELENGKENG (Dimocarpus
longan Lour.) TERHADAP PENURUNAN KADAR KOLESTEROL
TOTAL DAN LDL PADA HAMSTER SYRIAN JANTAN
HIPERLIPIDEMIA
ispublished: pub
subjects: R
subjects: RS
divisions: 48201
abstract: Daun kelengkeng (Dimocarpus longan Lour.) mengandung senyawa flavonoid,
saponin, tanin, dan steroid yang diduga berkhasiat sebagai antihiperlipidemia.
Penelitian ini bertujuan untuk mengetahui aktivitas fraksi daun kelengkeng
terhadap penurunan kadar kolesterol total dan low density lipoprotein (LDL) pada
hamster hiperlipidemia. Digunakan hamster syrian jantan yang diinduksi dengan
pakan tinggi lemak sebanyak 7 kelompok yaitu kelompok normal yang tidak
diinduksi dan tidak diberikan sediaan uji, kelompok positif (atorvastatin) dengan
dosis 2,47 mg/kgBB, kelompok negatif yang dinduksi dan diberikan Na-CMC,
kelompok fraksi n-heksana, kelompok fraksi etil asetat, kelompok fraksi n-butanol,
dan kelompok fraksi air dengan dosis 158,6132 mg/kgBB. Sampel darah diambil
kemudian dilakukan pengukuran kadar kolesterol total dan LDL pada serum darah.
Data dianalisis menggunakan ANOVA satu arah dilanjutkan dengan uji Tukey.
Hasil penelitian menunjukkan bahwa fraksi daun kelengkeng memiliki aktivitas
antihiperlipidemia dimana dapat menurunkan kadar kolesterol total dan LDL
dengan persentase penurunan tertinggi pada fraksi n-butanol sebesar 48,49% dan
47,99%.
Kata kunci: Daun kelengkeng, hiperlipidemia, kolesterol total, LDL.
date: 2021
date_type: completed
full_text_status: public
institution: Universitas Muhammadiyah Prof. DR. HAMKA
department: Fakultas Farmasi dan Sains
thesis_type: bachelor
thesis_name: bphil
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citation:   Fitriani, Dhelia Nur dan Dwitiyanti, Dwitiyanti dan Hikmawanti, Ni Putu Ermi  (2021) JI AKTIVITAS FRAKSI-FRAKSI DAUN KELENGKENG (Dimocarpus longan Lour.) TERHADAP PENURUNAN KADAR KOLESTEROL TOTAL DAN LDL PADA HAMSTER SYRIAN JANTAN HIPERLIPIDEMIA.  Bachelor thesis, Universitas Muhammadiyah Prof. DR. HAMKA.   
document_url: http://repository.uhamka.ac.id/id/eprint/20965/1/FS03-210275.pdf