eprintid: 18310
rev_number: 8
eprint_status: archive
userid: 3858
dir: disk0/00/01/83/10
datestamp: 2023-02-02 03:07:58
lastmod: 2023-02-02 03:07:58
status_changed: 2023-02-02 03:07:58
type: thesis
metadata_visibility: show
creators_name: Faiza, Isma Rahmah
creators_name: Lestari, Pramulani Mulya
creators_name: YATI, KORI
title: PENGARUH HPMC SEBAGAI POLIMER TERHADAP LAJU DIFUSI
SEDIAAN PATCH MINYAK CENGKEH (Syzygium aromaticum) PADA
PENYAKIT PERIODONTAL
ispublished: pub
subjects: R
subjects: RS
divisions: 48201
abstract: Penyakit periodontal adalah penyakit inflamasi yang menyerang jaringan
pendukung gigi. Minyak cengkeh berasal dari tanaman cengkeh memiliki aktivitas
antiinflamasi karena mengandung senyawa eugenol. Apabila minyak cengkeh
digunakan secara langsung dapat mengganggu kenyamanan sehingga dibuat
sediaan Patch. Penelitian ini bertujuan untuk mengetahui pengaruh variasi
konsentrasi polimer HPMC terhadap laju difusi sediaan patch minyak cengkeh
(Syzygium aromaticum) dengan menggunakan sel difusi franz termodifikasi.
Sedian patch dibuat dengan metode solvent casting dalam 3 formula variasi
konsentrasi HPMC (1%, 1,5%, 2%). Dilakukan uji sifat fisik yang menunjukkan
patch elastis berwarna putih tulang dan uji difusi menunjukan tiap formula
mengikuti kinetika pelepasan orde Higuchi. Penggunaan variasi konsentrasi
HPMC yang digunakan pada polimer patch menunjukkan bahwa F2 dengan
konsentrasi HPMC 1,5% dapat meningkatkan laju difusi sediaan patch minyak
cengkeh.
Kata kunci: Minyak Cengkeh, Patch Mukoadhesif, HPMC, Uji Difusi, Eugeno
date: 2020
date_type: completed
full_text_status: public
institution: Universitas Muhammadiyah Prof . DR. HAMKA
department: Fakultas farmasi dan sains
thesis_type: bachelor
thesis_name: bphil
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citation:   Faiza, Isma Rahmah dan Lestari, Pramulani Mulya dan YATI, KORI  (2020) PENGARUH HPMC SEBAGAI POLIMER TERHADAP LAJU DIFUSI SEDIAAN PATCH MINYAK CENGKEH (Syzygium aromaticum) PADA PENYAKIT PERIODONTAL.  Bachelor thesis, Universitas Muhammadiyah Prof . DR. HAMKA.   
document_url: http://repository.uhamka.ac.id/id/eprint/18310/1/S03-200184.pdf