eprintid: 18277
rev_number: 7
eprint_status: archive
userid: 3858
dir: disk0/00/01/82/77
datestamp: 2023-02-01 09:38:47
lastmod: 2023-02-01 09:38:47
status_changed: 2023-02-01 09:38:47
type: thesis
metadata_visibility: show
creators_name: Wafa L, Onisa Triwal
creators_name: Hanani, Endang
creators_name: Wardani, Elly
title: UJI AKTIVITAS ANTIHIPERLIPIDEMIA EKSTRAK ETANOL 70% DAUN
ASAMLONDO (Pithecellobium dulce (Roxb.) Benth.) TERHADAP PENURUNAN
KADAR KOLESTEROL TOTAL DAN LDL PADA HAMSTER
SYRIAN JANTAN (Mesocricetus auratus) HIPERLIPIDEMIA
ispublished: pub
subjects: RS
divisions: 48201
abstract: Phitecellobium dulce (Roxb.) Benth. atau dikenal dengan asam londo merupakan
tanaman yang mengandung flavonoid dan digunakan sebagai antihiperlipidemia.
Tujuan penelitian ini adalah untuk mengetahui aktivitas ekstrak etanol 70% daun
asam londo terhadap penurunan kadar kolesterol total dan LDL pada hamster
hiperlipidemia. Hamster Syirian jantan dibagi dalam 6 kelompok perlakuan
masing-masing terdiri dari 4 hamster: kelompok I (normal), kelompok II (negatif),
kelompok III (atorvastatin), kelompok IV (dosis 1), Kelompok V (dosis 2), dan
kelompok VI (dosis 3). Data persentase penurunan kadar kolesterol total dan LDL
dianalisis menggunakan uji ANOVA one way dan dilanjutkan dengan uji Tukey.
Hasil penelitian menunjukkan bahwa dari ketiga dosis memiliki aktivitas
antihiperlipidemia yang dilihat dari adanya perbedaan bermakna pada kelompok
negatif dengan nilai P<0,05. Dosis 3 (480 mg/kgBB) dapat menurunkan kadar
kolesterol total sebesar 64,12% yang tidak berbeda bermakna (P>0,05) dengan
atorvastatin sebesar 52,97% dan menurunkan kadar LDL sebesar 72,44% yang
tidak berbeda bermakna (P>0,05) dengan atorvastatin sebesar 58,40%.
 Kata Kunci: Asam londo, hamster, hiperlipidemia
date: 2019
date_type: completed
full_text_status: public
institution: Universitas Muhammadiyah Prof. DR. HAMKA
department: Fakultas farmasi dan sains
thesis_type: bachelor
thesis_name: bphil
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citation:   Wafa L, Onisa Triwal dan Hanani, Endang dan Wardani, Elly  (2019) UJI AKTIVITAS ANTIHIPERLIPIDEMIA EKSTRAK ETANOL 70% DAUN ASAMLONDO (Pithecellobium dulce (Roxb.) Benth.) TERHADAP PENURUNAN KADAR KOLESTEROL TOTAL DAN LDL PADA HAMSTER SYRIAN JANTAN (Mesocricetus auratus) HIPERLIPIDEMIA.  Bachelor thesis, Universitas Muhammadiyah Prof. DR. HAMKA.   
document_url: http://repository.uhamka.ac.id/id/eprint/18277/1/S03-200078.pdf