eprintid: 15935
rev_number: 6
eprint_status: archive
userid: 1558
dir: disk0/00/01/59/35
datestamp: 2022-07-26 10:37:36
lastmod: 2022-07-26 10:37:36
status_changed: 2022-07-26 10:37:36
type: article
metadata_visibility: show
creators_name: Siska, Siska
creators_name: Bariroh, Tahyatul
creators_id: siska@uhamka.ac.id
creators_orcid: 0000-0003-4830-9261
creators_orcid: 0000-0002-9233-1557
title: Anti-obesity Potency of Chili Extract in Male White Rat
ispublished: pub
subjects: RM
divisions: 48901
abstract: Obesity is a global epidemic for non-communicable diseases characterized by a body mass index more 
than 30 kg/m2
. Epidemiological data show that consuming foods containing capsaicin, the main active 
compound and causes a spicy taste in chili associated with a decrease in the prevalence of obesity. This 
study aims to determine the effect of consumption chili on lipid profile of rats fed high-fat diet and their 
potential as anti-obesity. Treatment was conducted on 24 male Sprague-Dawley rats and divided into 
6 groups namely the regular group (N) was given a standard diet and the group that was given a high�fat diet (PTL) and varied with a dose of 0.5 g/kg BW. Every 14 days of treatment, the weight of the 
rats was weighed, and blood was taken retro-orbital to obtain the serum. The rat serum was tested for 
total cholesterol (TC), triglycerides, LDL, and HDL through the colorimetric method. The levels were 
assessed using a clinical spectrophotometer. The results showed a decrease in weight, LDL, increase 
HDL (p<0.05), decrease in TC, triglyceride (p>0.05). This showed chili extract has the potential as an 
anti-obesity with parameters of measuring lipid profile and weight but needs dose adjuster and timing 
of extract administration.
date: 2022-06-30
date_type: published
publisher: Universitas Padjadjaran
official_url: http://jurnal.unpad.ac.id/ijpst/index
full_text_status: public
publication: Anti-obesity Potency of Chili Extract in Male White Rat
volume: 9
number: 2
pagerange: 83-93
refereed: TRUE
issn: 2356-1971
citation:   Siska, Siska dan Bariroh, Tahyatul  (2022) Anti-obesity Potency of Chili Extract in Male White Rat.  Anti-obesity Potency of Chili Extract in Male White Rat, 9 (2).  pp. 83-93.  ISSN 2356-1971     
document_url: http://repository.uhamka.ac.id/id/eprint/15935/1/SISKA_IJPST_2022.pdf