%0 Journal Article
%@ 2356-1971
%A Siska, Siska
%A Bariroh, Tahyatul
%D 2022
%F repository:15935
%I Universitas Padjadjaran
%J Anti-obesity Potency of Chili Extract in Male White Rat
%N 2
%P 83-93
%T Anti-obesity Potency of Chili Extract in Male White Rat
%U http://repository.uhamka.ac.id/id/eprint/15935/
%V 9
%X Obesity is a global epidemic for non-communicable diseases characterized by a body mass index more   than 30 kg/m2  . Epidemiological data show that consuming foods containing capsaicin, the main active   compound and causes a spicy taste in chili associated with a decrease in the prevalence of obesity. This   study aims to determine the effect of consumption chili on lipid profile of rats fed high-fat diet and their   potential as anti-obesity. Treatment was conducted on 24 male Sprague-Dawley rats and divided into   6 groups namely the regular group (N) was given a standard diet and the group that was given a high�fat diet (PTL) and varied with a dose of 0.5 g/kg BW. Every 14 days of treatment, the weight of the   rats was weighed, and blood was taken retro-orbital to obtain the serum. The rat serum was tested for   total cholesterol (TC), triglycerides, LDL, and HDL through the colorimetric method. The levels were   assessed using a clinical spectrophotometer. The results showed a decrease in weight, LDL, increase   HDL (p<0.05), decrease in TC, triglyceride (p>0.05). This showed chili extract has the potential as an   anti-obesity with parameters of measuring lipid profile and weight but needs dose adjuster and timing   of extract administration.