relation: http://repository.uhamka.ac.id/id/eprint/15935/ title: Anti-obesity Potency of Chili Extract in Male White Rat creator: Siska, Siska creator: Bariroh, Tahyatul subject: RM Therapeutics. Pharmacology description: Obesity is a global epidemic for non-communicable diseases characterized by a body mass index more than 30 kg/m2 . Epidemiological data show that consuming foods containing capsaicin, the main active compound and causes a spicy taste in chili associated with a decrease in the prevalence of obesity. This study aims to determine the effect of consumption chili on lipid profile of rats fed high-fat diet and their potential as anti-obesity. Treatment was conducted on 24 male Sprague-Dawley rats and divided into 6 groups namely the regular group (N) was given a standard diet and the group that was given a high�fat diet (PTL) and varied with a dose of 0.5 g/kg BW. Every 14 days of treatment, the weight of the rats was weighed, and blood was taken retro-orbital to obtain the serum. The rat serum was tested for total cholesterol (TC), triglycerides, LDL, and HDL through the colorimetric method. The levels were assessed using a clinical spectrophotometer. The results showed a decrease in weight, LDL, increase HDL (p<0.05), decrease in TC, triglyceride (p>0.05). This showed chili extract has the potential as an anti-obesity with parameters of measuring lipid profile and weight but needs dose adjuster and timing of extract administration. publisher: Universitas Padjadjaran date: 2022-06-30 type: Article type: PeerReviewed format: text language: en identifier: http://repository.uhamka.ac.id/id/eprint/15935/1/SISKA_IJPST_2022.pdf identifier: Siska, Siska dan Bariroh, Tahyatul (2022) Anti-obesity Potency of Chili Extract in Male White Rat. Anti-obesity Potency of Chili Extract in Male White Rat, 9 (2). pp. 83-93. ISSN 2356-1971 relation: http://jurnal.unpad.ac.id/ijpst/index