The Best Extraction Methods of Wet and Dry Papaja (Carica papaja L.) Seed as Anthelmintics Effect on Ascardia galli

Gusmayadi, IndingdanPriyanto, PriyantodanDwitiyanti, Dwitiyanti The Best Extraction Methods of Wet and Dry Papaja (Carica papaja L.) Seed as Anthelmintics Effect on Ascardia galli. Proceeding of ICPSP. ISSN 978-602-50854-1-3

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Abstract

Papaya seed in previous research is known has an effect of anthelmintic on Ascardia galli, but the effect of papaya seed just by traditional method i.e. boiling in water. To get the effective extraction methods, it still needs to be done many kinds of extraction methods of papaya seed, to know which one is the best. Methods of extraction in this research were maceration, soxhletation, and ultrasonic digestion. We used two kinds of papaya seed: wet and dry, using solvent: water, 70% ethanol, and n-hexane. Data of anthelmintic activity were percentage of worm death, LD50, and relative potential to pyrantel pamoate as positive control. The result showed that the best extraction method of papaya seed which had highest in vitro effect on Ascardia galli worm was maceration method with 70% ethanol as solvent of wet papaja seed. It killed 60% of worm with LD50 9.36 mg and its relative potential is 0.66 times pyrantel pamoate.

Item Type: Article
Subjects: Q Science > Q Science (General)
Depositing User: ST Bahar Sobari
Date Deposited: 21 Feb 2020 09:52
Last Modified: 21 Feb 2020 09:52
URI: http://repository.uhamka.ac.id/id/eprint/915

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